TY  - JOUR
AU  - Filippidou, Maria
AU  - Glentis, Stavros
AU  - Binenbaum, Ilona
AU  - Sill, Martin
AU  - Roka, Kleoniki
AU  - Vlachou, Antonia
AU  - Avgerinou, Georgia
AU  - Ecker, Jonas
AU  - Selt, Florian
AU  - Hasselblatt, Martin
AU  - Blattner-Johnson, Mirjam
AU  - Schramm, Kathrin
AU  - Trougkou, Clio
AU  - Doganis, Dimitrios
AU  - Katzilakis, Nikolaos
AU  - Ridola, Vita
AU  - Papakonstantinou, Evgenia
AU  - Papadakis, Vassilios
AU  - Hatzipantelis, Emmanouel
AU  - Kokkinou, Eleftheria
AU  - Pons, Roser
AU  - Kanaka-Gantenbein, Christina
AU  - Sturm, Dominik
AU  - Hirsch, Steffen
AU  - Dikow, Nicola
AU  - Pajtler, Kristian
AU  - van Tilburg, Cornelis Martinus
AU  - Frühwald, Michael C.
AU  - Milde, Till
AU  - Witt, Olaf
AU  - Jones, David
AU  - von Deimling, Andreas
AU  - Sahm, Felix
AU  - Stefanaki, Kalliopi
AU  - Pfister, Stefan
AU  - Kattamis, Antonis
TI  - The impact of methylome analysis on the diagnosis and treatment of CNS tumours in children and adolescents: A population-based study in Greece
JO  - EJC paediatric oncology
VL  - 4
SN  - 2772-610X
CY  - [Amsterdam]
PB  - Elsevier B.V.
M1  - DKFZ-2024-02087
SP  - 100198
PY  - 2024
N1  - #EA:B062#LA:B062#
AB  - Background: The recently published WHO classification of central nervous system (CNS) tumours recognizes DNAmethylation profiling as a desirable and, for some diagnoses, essential diagnostic tool adjunctive to conventionalhistopathology. DNA methylation profiling is not routinely available in many countries, including Greece.Methods: In this collaborative study, we report the DNA methylation results in a series of children and adolescentswith CNS tumours in Greece (2018–2023). In total, 130 tumour samples were analyzed using the latest applicable version of the Heidelberg brain tumour classifier.Results: Upon initial analysis, 80 
LB  - PUB:(DE-HGF)16
DO  - DOI:10.1016/j.ejcped.2024.100198
UR  - https://inrepo02.dkfz.de/record/294066
ER  -