000294338 001__ 294338 000294338 005__ 20250203105546.0 000294338 0247_ $$2doi$$a10.1002/mrm.30359 000294338 0247_ $$2pmid$$apmid:39462473 000294338 0247_ $$2ISSN$$a1522-2594 000294338 0247_ $$2ISSN$$a0740-3194 000294338 037__ $$aDKFZ-2024-02171 000294338 041__ $$aEnglish 000294338 082__ $$a610 000294338 1001_ $$aKrueger, Felix$$b0 000294338 245__ $$aDeep learning-based whole-brain B1 +-mapping at 7T. 000294338 260__ $$aNew York, NY [u.a.]$$bWiley-Liss$$c2025 000294338 3367_ $$2DRIVER$$aarticle 000294338 3367_ $$2DataCite$$aOutput Types/Journal article 000294338 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1738576495_6792 000294338 3367_ $$2BibTeX$$aARTICLE 000294338 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000294338 3367_ $$00$$2EndNote$$aJournal Article 000294338 500__ $$a#LA:E020# / 2025 Apr;93(4):1700-1711 000294338 520__ $$aThis study investigates the feasibility of using complex-valued neural networks (NNs) to estimate quantitative transmit magnetic RF field (B1 +) maps from multi-slice localizer scans with different slice orientations in the human head at 7T, aiming to accelerate subject-specific B1 +-calibration using parallel transmission (pTx).Datasets containing channel-wise B1 +-maps and corresponding multi-slice localizers were acquired in axial, sagittal, and coronal orientation in 15 healthy subjects utilizing an eight-channel pTx transceiver head coil. Training included five-fold cross-validation for four network configurations: NN cx tra $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{tra}} $$ used transversal, NN cx sag $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{sag}} $$ sagittal, NN cx cor $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{cor}} $$ coronal data, and NN cx all $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{all}} $$ was trained on all slice orientations. The resulting maps were compared to B1 +-reference scans using different quality metrics. The proposed network was applied in-vivo at 7T in two unseen test subjects using dynamic kt-point pulses.Predicted B1 +-maps demonstrated a high similarity with measured B1 +-maps across multiple orientations. The estimation matched the reference with a mean relative error in the magnitude of (2.70 ± 2.86)% and mean absolute phase difference of (6.70 ± 1.99)° for transversal, (1.82 ± 0.69)% and (4.25 ± 1.62)° for sagittal ( NN cx sag $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{sag}} $$ ), as well as (1.33 ± 0.27)% and (2.66 ± 0.60)° for coronal slices ( NN cx cor $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{cor}} $$ ) considering brain tissue. NN cx all $$ {\mathrm{NN}}_{\mathrm{cx}}^{\mathrm{all}} $$ trained on all orientations enables a robust prediction of B1 +-maps across different orientations. Achieving a homogenous excitation over the whole brain for an in-vivo application displayed the approach's feasibility.This study demonstrates the feasibility of utilizing complex-valued NNs to estimate multi-slice B1 +-maps in different slice orientations from localizer scans in the human brain at 7T. 000294338 536__ $$0G:(DE-HGF)POF4-315$$a315 - Bildgebung und Radioonkologie (POF4-315)$$cPOF4-315$$fPOF IV$$x0 000294338 588__ $$aDataset connected to CrossRef, PubMed, , Journals: inrepo02.dkfz.de 000294338 650_7 $$2Other$$a7 tesla 000294338 650_7 $$2Other$$aB1+‐mapping 000294338 650_7 $$2Other$$abrain 000294338 650_7 $$2Other$$adeep learning 000294338 650_7 $$2Other$$aparallel transmission 000294338 7001_ $$00000-0003-3618-9610$$aAigner, Christoph Stefan$$b1 000294338 7001_ $$00009-0001-1956-3757$$aLutz, Max$$b2 000294338 7001_ $$00000-0001-5411-7288$$aRiemann, Layla Tabea$$b3 000294338 7001_ $$aDegenhardt, Katja$$b4 000294338 7001_ $$00009-0002-8625-8522$$aHadjikiriakos, Kimon$$b5 000294338 7001_ $$00000-0002-0862-8973$$aZimmermann, Felix Frederik$$b6 000294338 7001_ $$00000-0002-2734-1409$$aHammernik, Kerstin$$b7 000294338 7001_ $$00000-0003-3100-1092$$aSchulz-Menger, Jeanette$$b8 000294338 7001_ $$00000-0003-1310-2631$$aSchaeffter, Tobias$$b9 000294338 7001_ $$0P:(DE-He78)19e2d877276b0e5eec11cdfc1789a55e$$aSchmitter, Sebastian$$b10$$eLast author$$udkfz 000294338 773__ $$0PERI:(DE-600)1493786-4$$a10.1002/mrm.30359$$gp. mrm.30359$$n4$$p1700-1711$$tMagnetic resonance in medicine$$v93$$x1522-2594$$y2025 000294338 909CO $$ooai:inrepo02.dkfz.de:294338$$pVDB 000294338 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)19e2d877276b0e5eec11cdfc1789a55e$$aDeutsches Krebsforschungszentrum$$b10$$kDKFZ 000294338 9131_ $$0G:(DE-HGF)POF4-315$$1G:(DE-HGF)POF4-310$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lKrebsforschung$$vBildgebung und Radioonkologie$$x0 000294338 9141_ $$y2024 000294338 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2023-10-21$$wger 000294338 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2023-10-21$$wger 000294338 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bMAGN RESON MED : 2022$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2023-10-21 000294338 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-10-21 000294338 9202_ $$0I:(DE-He78)E020-20160331$$kE020$$lE020 Med. 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