%0 Journal Article
%A Reichmann, Robin
%A Nimptsch, Katharina
%A Pischon, Tobias
%A Gunter, Marc J
%A Jenab, Mazda
%A Eriksen, Anne Kirstine
%A Tjonneland, Anne
%A Janke, Jürgen
%A Katzke, Verena
%A Kaaks, Rudolf
%A Schulze, Matthias B
%A Eichelmann, Fabian
%A Masala, Giovanna
%A Sieri, Sabina
%A Pasanisi, Fabrizio
%A Tumino, Rosario
%A Giraudo, Maria Teresa
%A Rothwell, Joseph
%A Severi, Gianluca
%A Jakszyn, Paula
%A Sanchez-Perez, Maria Jose
%A Amiano, Pilar
%A Colorado-Yohar, Sandra M
%A Guevara, Marcela
%A van Guelpen, Bethany
%A Aglago, Elom K
%A Heath, Alicia K
%A Smith-Byrne, Karl
%A Weiderpass, Elisabete
%A Aleksandrova, Krasimira
%T Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort.
%J International journal of cancer
%V 156
%N 5
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2024-02278
%P 930-942
%D 2025
%Z 2025 Mar 1;156(5):930-942
%X Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence from human research has been scant. We, therefore, explored the association of pre-diagnostic circulating LCN2 concentrations with incident colorectal cancer (CRC) in a nested case-control study within the in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. LCN2 was measured in 1267 incident CRC cases matched to 1267 controls using incidence density sampling. Conditional logistic regression was used to estimate incidence rate ratios (IRRs) and 95
%K EPIC (Other)
%K colorectal cancer (Other)
%K immunity (Other)
%K lipocalin 2 (Other)
%K metabolism (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39511728
%R 10.1002/ijc.35205
%U https://inrepo02.dkfz.de/record/294453