TY  - JOUR
AU  - Reichmann, Robin
AU  - Nimptsch, Katharina
AU  - Pischon, Tobias
AU  - Gunter, Marc J
AU  - Jenab, Mazda
AU  - Eriksen, Anne Kirstine
AU  - Tjonneland, Anne
AU  - Janke, Jürgen
AU  - Katzke, Verena
AU  - Kaaks, Rudolf
AU  - Schulze, Matthias B
AU  - Eichelmann, Fabian
AU  - Masala, Giovanna
AU  - Sieri, Sabina
AU  - Pasanisi, Fabrizio
AU  - Tumino, Rosario
AU  - Giraudo, Maria Teresa
AU  - Rothwell, Joseph
AU  - Severi, Gianluca
AU  - Jakszyn, Paula
AU  - Sanchez-Perez, Maria Jose
AU  - Amiano, Pilar
AU  - Colorado-Yohar, Sandra M
AU  - Guevara, Marcela
AU  - van Guelpen, Bethany
AU  - Aglago, Elom K
AU  - Heath, Alicia K
AU  - Smith-Byrne, Karl
AU  - Weiderpass, Elisabete
AU  - Aleksandrova, Krasimira
TI  - Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: Results from the EPIC cohort.
JO  - International journal of cancer
VL  - 156
IS  - 5
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2024-02278
SP  - 930-942
PY  - 2025
N1  - 2025 Mar 1;156(5):930-942
AB  - Experimental research has uncovered lipocalin 2 (LCN2) as a novel biomarker implicated in the modulation of intestinal inflammation, metabolic homeostasis, and colon carcinogenesis. However, evidence from human research has been scant. We, therefore, explored the association of pre-diagnostic circulating LCN2 concentrations with incident colorectal cancer (CRC) in a nested case-control study within the in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. LCN2 was measured in 1267 incident CRC cases matched to 1267 controls using incidence density sampling. Conditional logistic regression was used to estimate incidence rate ratios (IRRs) and 95
KW  - EPIC (Other)
KW  - colorectal cancer (Other)
KW  - immunity (Other)
KW  - lipocalin 2 (Other)
KW  - metabolism (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39511728
DO  - DOI:10.1002/ijc.35205
UR  - https://inrepo02.dkfz.de/record/294453
ER  -