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| Home > Publications database > Associations of milk, dairy products, calcium and vitamin D intake with risk of developing Parkinson´s disease within the EPIC4ND cohort. > print |
| 001 | 294804 | ||
| 005 | 20241216114404.0 | ||
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| 100 | 1 | _ | |a Gröninger, Mareike |0 P:(DE-He78)368cffed46c9727340333e3279d0f2c5 |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a Associations of milk, dairy products, calcium and vitamin D intake with risk of developing Parkinson´s disease within the EPIC4ND cohort. |
| 260 | _ | _ | |a Dordrecht [u.a.] |c 2024 |b Springer Science + Business Media B.V. |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 500 | _ | _ | |a #EA:C020#LA:C020# / 2024 Nov;39(11):1251-1265 |
| 520 | _ | _ | |a Literature indicates a potential association between dairy consumption and risk of Parkinson´s disease (PD), especially among men, yet the results remain inconclusive. We investigated this association in a large prospective European cohort. Dietary and non-dietary data was collected from 183,225 participants of the EPIC-for-Neurodegenerative-Diseases (EPIC4ND) cohort, a sub-cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Crude and multivariable-adjusted Cox proportional hazards models were employed to examine potential associations between baseline dietary intake of dairy, calcium and vitamin D with incident PD risk. No relationship was observed between dairy consumption (HR 1.07, 95% CI 0.82-1.39), individual dairy products (milk: HR 0.95, 95% CI 0.73-1.23; yogurt: HR 1.03, 95% CI 0.82-1.29; cheese: HR 1.13, 95% CI 0.85-1.51), or vitamin D (HR 1.08, 95% CI 0.80-1.45) with PD risk. However, we observed a risk-increasing association with higher calcium intakes (HR 1.33, 95% CI 1.00-1.78, p for trend = 0.031), which was more pronounced in men (HR 1.50, 95% CI 1.00-2.25, p for trend = 0.044) and in ever smokers (HR 1.64, 95% CI 1.06-2.53, p for trend = 0.014). No compelling evidence was found for an association between dairy products or vitamin D intake and PD risk indicating a potentially limited relevance of dairy intake in PD risk than previously described. Our observations of a positive association between dietary calcium intake and PD risk in men and in ever smokers require further validation. |
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| 650 | _ | 7 | |a Calcium |2 Other |
| 650 | _ | 7 | |a Dairy |2 Other |
| 650 | _ | 7 | |a EPIC |2 Other |
| 650 | _ | 7 | |a Parkinson´s disease |2 Other |
| 650 | _ | 7 | |a Vitamin D |2 Other |
| 700 | 1 | _ | |a Sabin, Jara |0 P:(DE-He78)18b6fde740d8238c47673a8a50a4d92b |b 1 |u dkfz |
| 700 | 1 | _ | |a Kaaks, Rudolf |0 P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a |b 2 |u dkfz |
| 700 | 1 | _ | |a Amiano, Pilar |0 0000-0003-3986-7026 |b 3 |
| 700 | 1 | _ | |a Aune, Dagfinn |0 0000-0002-4533-1722 |b 4 |
| 700 | 1 | _ | |a Castro, Natalia Cabrera |b 5 |
| 700 | 1 | _ | |a Guevara, Marcela |b 6 |
| 700 | 1 | _ | |a Hansen, Johnni |0 0000-0002-9342-2725 |b 7 |
| 700 | 1 | _ | |a Homann, Jan |0 0000-0003-2791-7065 |b 8 |
| 700 | 1 | _ | |a Masala, Giovanna |b 9 |
| 700 | 1 | _ | |a Nicolas, Geneviève |0 0000-0001-7871-7149 |b 10 |
| 700 | 1 | _ | |a Peters, Susan |0 0000-0001-5662-1971 |b 11 |
| 700 | 1 | _ | |a Sacerdote, Carlotta |0 0000-0002-8008-5096 |b 12 |
| 700 | 1 | _ | |a Sánchez, Maria-Jose |b 13 |
| 700 | 1 | _ | |a De Magistris, Maria Santucci |b 14 |
| 700 | 1 | _ | |a Sieri, Sabina |b 15 |
| 700 | 1 | _ | |a Vermeulen, Roel |b 16 |
| 700 | 1 | _ | |a Zhao, Yujia |0 0000-0002-5275-0036 |b 17 |
| 700 | 1 | _ | |a Lill, Christina M |b 18 |
| 700 | 1 | _ | |a Katzke, Verena |0 P:(DE-He78)fb68a9386399d72d84f7f34cfc6048b4 |b 19 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1007/s10654-024-01183-9 |0 PERI:(DE-600)2004992-4 |n 11 |p 1251-1265 |t European journal of epidemiology |v 39 |y 2024 |x 0393-2990 |
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