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@ARTICLE{Porcari:294847,
      author       = {S. Porcari and B. H. Mullish and F. Asnicar and S. C. Ng
                      and L. Zhao and R. Hansen and P. W. O'Toole and J. Raes and
                      G. Hold and L. Putignani and C. L. Hvas and G. Zeller and O.
                      Koren and H. Tun and M. Valles-Colomer and M. C. Collado and
                      M. Fischer and J. Allegretti and T. Iqbal and B. Chassaing
                      and J. Keller and S. M. Baunwall and M. Abreu and G. Barbara
                      and F. Zhang and F. R. Ponziani and S. P. Costello and S.
                      Paramsothy and D. Kao and C. Kelly and J. Kupcinskas and I.
                      Youngster and F. Franceschi and S. Khanna and M. Vehreschild
                      and A. Link and F. De Maio and E. Pasolli and A. B. Miguez
                      and P. Brigidi and B. Posteraro and F. Scaldaferri and M. R.
                      Stojanovic and F. Megraud and P. Malfertheiner and L.
                      Masucci and M. Arumugam and N. Kaakoush and E. Segal and J.
                      Bajaj and R. Leong and J. Cryan and R. K. Weersma and R.
                      Knight and F. Guarner and F. Shanahan and P. D. Cani and E.
                      Elinav$^*$ and M. Sanguinetti and W. M. de Vos and E.
                      El-Omar and J. Dorè and J. Marchesi and H. Tilg and H.
                      Sokol and N. Segata and G. Cammarota and A. Gasbarrini and
                      G. Ianiro},
      title        = {{I}nternational consensus statement on microbiome testing
                      in clinical practice.},
      journal      = {The lancet / Gastroenterology $\&$ Hepatology},
      volume       = {10},
      number       = {2},
      issn         = {2468-1253},
      address      = {London},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2024-02557},
      pages        = {154-167},
      year         = {2025},
      note         = {Volume 10, Issue 2, February 2025, Pages 154-167},
      abstract     = {There is growing interest in the potential exploitation of
                      the gut microbiome as a diagnostic tool in medicine, but
                      evidence supporting its clinical usefulness is scarce. An
                      increasing number of commercial providers offer
                      direct-to-consumer microbiome diagnostic tests without any
                      consensus on their regulation or any proven value in
                      clinical practice, which could result in considerable waste
                      of individual and health-care resources and potential
                      drawbacks in the clinical management of patients. We
                      convened an international multidisciplinary expert panel to
                      standardise best practices of microbiome testing for
                      clinical implementation, including recommendations on
                      general principles and minimum requirements for their
                      provision, indications, pre-testing protocols, method of
                      analyses, reporting of results, and potential clinical
                      value. We also evaluated current knowledge gaps and future
                      directions in this field. We aimed to establish a framework
                      to regulate the provision of microbiome testing and minimise
                      the use of inappropriate tests and pave the way for the
                      evidence-based development and use of human microbiome
                      diagnostics in clinical medicine.},
      subtyp        = {Review Article},
      cin          = {D480},
      ddc          = {610},
      cid          = {I:(DE-He78)D480-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39647502},
      doi          = {10.1016/S2468-1253(24)00311-X},
      url          = {https://inrepo02.dkfz.de/record/294847},
}