% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Bamberg:295833,
      author       = {F. Bamberg and C. L. Schlett and S. Caspers and S. Ringhof
                      and M. Günther and J. G. Hirsch and J. Rüdebusch and P.
                      Miklánková and N. Bittner and C. Jockwitz and M. Forsting
                      and N. Hosten and R. Kaaks$^*$ and H.-U. Kauczor and T.
                      Kroenke and T. Niendorf and A. Peters and T. Pischon and A.
                      Stang and K. Berger and H. Völzke and N. I. Consortium},
      title        = {{B}aseline {MRI} {E}xamination in the {NAKO} {H}ealth
                      {S}tudy—{F}indings on {F}easibility, {P}articipation and
                      {D}ropout {R}ates, {C}omfort, and {I}mage {Q}uality.},
      journal      = {Deutsches Ärzteblatt international},
      volume       = {121},
      number       = {18},
      issn         = {1866-0452},
      address      = {Köln},
      publisher    = {Dt. Ärzte-Verl.},
      reportid     = {DKFZ-2024-02653},
      pages        = {587-593},
      year         = {2024},
      abstract     = {Magnetic resonance imaging (MRI) yields important
                      information on the development and current status of many
                      different diseases. Whole-body MRI was accordingly made a
                      part of the multicenter, population-based NAKO Health Study.
                      The present analysis concerns the feasibility of the
                      baseline MRI examination and various aspects of quality
                      assurance over the period 2014-2019.32 252 participants in
                      the NAKO Health Study, aged 20 to 74, who had no
                      contraindication to MRI were invited to undergo scanning in
                      one of five MRI study centers across Germany. The whole-body
                      MRI scan took about one hour and consisted of sequences for
                      the visualization of structural and functional features of
                      the brain, musculoskeletal system, cardiovascular system,
                      and thoracoabdominal system. A comprehensive
                      quality-assurance assessment was carried out, with
                      evaluation of adverse events, the completeness of the MRI
                      protocols, the participants' subjective perceptions, and
                      image quality.31 578 participants $(97.9\%)$ were
                      successfully included in the MRI study. They reported a high
                      level of comfort and suffered no severe adverse events (mild
                      adverse events occurred in only four participants).
                      Depending on the imaging sequence, the image quality was
                      rated as excellent in $80.2\%$ to $96.8\%$ of cases. Quality
                      assessment with respect to structural features of the brain
                      revealed high consistency across study centers, as well as
                      with regard to age- and sex-based differences in brain
                      volume (men, 1203.81 ± 102.06 cm³; women, 1068.10 ± 86.69
                      cm³).Whole-body MRI was successfully implemented in the
                      NAKO baseline examination and was associated with high
                      patient comfort and very good image quality. The imaging
                      biomarkers of the brain confirmed previously observed
                      differences based on age and sex, underscoring the
                      feasibility of data pooling.},
      keywords     = {Humans / Magnetic Resonance Imaging: methods / Female /
                      Male / Adult / Middle Aged / Germany / Feasibility Studies /
                      Aged / Young Adult / Whole Body Imaging: methods},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39158357},
      doi          = {10.3238/arztebl.m2024.0151},
      url          = {https://inrepo02.dkfz.de/record/295833},
}