%0 Journal Article
%A Seum, Teresa
%A Hoffmeister, Michael
%A Brenner, Hermann
%T Risk-Adapted Starting Ages of Colorectal Cancer Screening for People With Diabetes or Metabolic Syndrome.
%J Alimentary pharmacology & therapeutics
%V 61
%N 4
%@ 0269-2813
%C Oxford
%I Blackwell Science
%M DKFZ-2024-02726
%P 675-681
%D 2025
%Z #EA:C070#LA:C070# / 2025 Feb;61(4):675-681
%X Individuals with diabetes and metabolic syndrome have an increased risk of colorectal cancer (CRC), suggesting earlier screening than the average-risk population may be warranted.To derive risk-adapted starting ages of CRC screening for people with diabetes or metabolic syndrome.We determined 5-year cumulative risks of CRC at individual ages between 30 and 50 across Europe (overall and individually for Germany, France, the UK and Italy) and North America (the United States and Canada) based on the GLOBOCAN 2022 database. Using risk estimates from meta-analyses (2020-2023), we derived the ages at which individuals with diabetes or metabolic syndrome reach the same CRC risk as the average-risk population at age 50 (aCR50) or 45 (aCR45).Individuals with diabetes were estimated to reach aCR50 at age 47 (95
%K colorectal cancer (Other)
%K diabetes (Other)
%K metabolic syndrome (Other)
%K risk‐adapted screening (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39686687
%R 10.1111/apt.18435
%U https://inrepo02.dkfz.de/record/295913