TY  - JOUR
AU  - Seum, Teresa
AU  - Hoffmeister, Michael
AU  - Brenner, Hermann
TI  - Risk-Adapted Starting Ages of Colorectal Cancer Screening for People With Diabetes or Metabolic Syndrome.
JO  - Alimentary pharmacology & therapeutics
VL  - 61
IS  - 4
SN  - 0269-2813
CY  - Oxford
PB  - Blackwell Science
M1  - DKFZ-2024-02726
SP  - 675-681
PY  - 2025
N1  - #EA:C070#LA:C070# / 2025 Feb;61(4):675-681
AB  - Individuals with diabetes and metabolic syndrome have an increased risk of colorectal cancer (CRC), suggesting earlier screening than the average-risk population may be warranted.To derive risk-adapted starting ages of CRC screening for people with diabetes or metabolic syndrome.We determined 5-year cumulative risks of CRC at individual ages between 30 and 50 across Europe (overall and individually for Germany, France, the UK and Italy) and North America (the United States and Canada) based on the GLOBOCAN 2022 database. Using risk estimates from meta-analyses (2020-2023), we derived the ages at which individuals with diabetes or metabolic syndrome reach the same CRC risk as the average-risk population at age 50 (aCR50) or 45 (aCR45).Individuals with diabetes were estimated to reach aCR50 at age 47 (95
KW  - colorectal cancer (Other)
KW  - diabetes (Other)
KW  - metabolic syndrome (Other)
KW  - risk‐adapted screening (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39686687
DO  - DOI:10.1111/apt.18435
UR  - https://inrepo02.dkfz.de/record/295913
ER  -