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@ARTICLE{Nguyen:296020,
      author       = {T. Nguyen and A. Koric and C. E. Chang and C. Barul and L.
                      Radoi and D. Serraino and M. P. Purdue and K. T. Kelsey and
                      M. D. McClean and E. Negri and V. Edefonti and K. Moysich
                      and Z.-F. Zhang and H. Morgenstern and F. Levi and T. L.
                      Vaughan and C. La Vecchia and W. Garavello and R. B. Hayes
                      and S. Benhamou and S. P. Schantz and G.-P. Yu and H.
                      Brenner$^*$ and S.-C. Chuang and P. Boffetta and M. Hashibe
                      and Y. A. Lee},
      title        = {{C}offee and tea consumption and the risk of head and neck
                      cancer: {A}n updated pooled analysis in the {I}nternational
                      {H}ead and {N}eck {C}ancer {E}pidemiology {C}onsortium.},
      journal      = {Cancer},
      volume       = {131},
      number       = {2},
      issn         = {0008-543X},
      address      = {New York, NY},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2024-02763},
      pages        = {e35620},
      year         = {2025},
      note         = {2025 Jan 15;131(2):e35620},
      abstract     = {The relations between coffee and tea consumption and head
                      and neck cancer (HNC) incidence are unclear. With increasing
                      global HNC burden, this study aims to examine the
                      association between coffee, tea, and HNC.A pooled analysis
                      of 9548 HNC cases and 15,783 controls from 14
                      individual-level case-control studies was conducted from the
                      International Head and Neck Cancer Epidemiology consortium.
                      Random-effects logistic regression was used to calculate
                      odds ratios (ORs) and $95\%$ confidence intervals (CIs) for
                      HNC and its subsites, adjusting for sociodemographic and
                      lifestyle factors.Compared to non-coffee drinkers, drinking
                      >4 cups of caffeinated coffee daily was inversely associated
                      with HNC (OR, 0.83; $95\%$ CI, 0.69-1.00), oral cavity (OR,
                      0.70; $95\%$ CI, 0.55-0.89), and oropharyngeal cancers (OR,
                      0.78; $95\%$ CI, 0.61-0.99). Drinking 3-4 cups of
                      caffeinated coffee was inversely associated with
                      hypopharyngeal cancer (OR, 0.59; $95\%$ CI, 0.39-0.91).
                      Drinking decaffeinated coffee and drinking between >0 to <1
                      cup daily were inversely associated with oral cavity cancer
                      (OR, 0.75; $95\%$ CI, 0.64-0.87 and OR, 0.66; $95\%$ CI,
                      0.54-0.81). Drinking tea was inversely associated with
                      hypopharyngeal cancer (OR, 0.71; $95\%$ CI, 0.59-0.87).
                      Daily tea consumption of >0 to ≤1 cup was inversely
                      associated with HNC (OR, 0.91; $95\%$ CI, 0.84-0.98) and
                      hypopharyngeal cancer (OR, 0.73; $95\%$ CI, 0.59-0.91), but
                      drinking >1 cup was associated with laryngeal cancer (OR,
                      1.38; $95\%$ CI, 1.09-1.74).These findings support reduced
                      HNC risk among coffee and tea drinkers. Future studies are
                      needed to address geographical differences in types of
                      coffee and tea to improve our understanding of the
                      association of coffee and tea and global HNC risk.},
      keywords     = {coffee and tea (Other) / head and neck cancer (Other) /
                      pooled analysis (Other)},
      cin          = {C070 / HD01 / C120},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)HD01-20160331 /
                      I:(DE-He78)C120-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39711146},
      doi          = {10.1002/cncr.35620},
      url          = {https://inrepo02.dkfz.de/record/296020},
}