TY - JOUR
AU - Schouten, Aniek E M
AU - Hiensch, Anouk E
AU - Frederix, Geert W J
AU - Monninkhof, Evelyn M
AU - Schmidt, Martina
AU - Clauss, Dorothea
AU - Gunasekara, Nadira
AU - Belloso, Jon
AU - Trevaskis, Mark
AU - Rundqvist, Helene
AU - Wiskemann, Joachim
AU - Müller, Jana
AU - Sweegers, Maike G
AU - Fremd, Carlo
AU - Altena, Renske
AU - Bijlsma, Rhodé M
AU - Sonke, Gabe
AU - Lahuerta, Ainhara
AU - Mann, G Bruce
AU - Francis, Prudence A
AU - Richardson, Gary
AU - Malter, Wolfram
AU - Kufel-Grabowska, Joanna
AU - van der Wall, Elsken
AU - Aaronson, Neil K
AU - Senkus, Elzbieta
AU - Urruticoechea, Ander
AU - Zopf, Eva M
AU - Bloch, Wilhelm
AU - Stuiver, Martijn M
AU - Wengstrom, Yvonne
AU - Steindorf, Karen
AU - van der Meulen, Miriam P
AU - May, Anne M
TI - Supervised Exercise for Patients With Metastatic Breast Cancer: A Cost-Utility Analysis Alongside the PREFERABLE-EFFECT Randomized Controlled Trial.
JO - Journal of clinical oncology
VL - 43
IS - 11
SN - 0732-183X
CY - Alexandria, Va.
PB - American Society of Clinical Oncology
M1 - DKFZ-2025-00130
SP - 1325-1336
PY - 2025
N1 - 2025 Apr 10;43(11):1325-1336
AB - To evaluate the cost utility of a 9-month supervised exercise program for patients with metastatic breast cancer (mBC), compared with control (usual care, supplemented with general activity advice and an activity tracker). Evidence on the cost-effectiveness of exercise for patients with mBC is essential for implementation in clinical practice and is currently lacking.A cost-utility analysis was performed alongside the multinational PREFERABLE-EFFECT randomized controlled trial, conducted in 8 centers across Europe and Australia. Patients with mBC (N = 357) were randomly assigned to either a 9-month, twice-weekly, supervised exercise group (EG) or control group (CG). Costs of the exercise program were calculated through a bottom-up approach. Other health care resource use, productivity losses, and quality of life were collected using country-adapted, self-reported questionnaires. Analyses were conducted from a societal perspective with a time horizon of 9 months. Costs were collected and reported in 2021 Euros (€1 =
LB - PUB:(DE-HGF)16
C6 - pmid:39805062
DO - DOI:10.1200/JCO-24-01441
UR - https://inrepo02.dkfz.de/record/296217
ER -