TY  - JOUR
AU  - Cocciardi, Sibylle
AU  - Saadati, Maral
AU  - Weiß, Nina
AU  - Späth, Daniela
AU  - Kapp-Schwoerer, Silke
AU  - Schneider, Isabelle
AU  - Meid, Annika
AU  - Gaidzik, Verena I
AU  - Skambraks, Sabrina
AU  - Fiedler, Walter
AU  - Kühn, Michael W M
AU  - Germing, Ulrich
AU  - Mayer, Karin T
AU  - Lübbert, Michael
AU  - Papaemmanuil, Elli
AU  - Thol, Felicitas
AU  - Heuser, Michael
AU  - Ganser, Arnold
AU  - Bullinger, Lars
AU  - Benner, Axel
AU  - Döhner, Hartmut
AU  - Döhner, Konstanze
TI  - Impact of myelodysplasia-related and additional gene mutations in intensively treated patients with NPM1-mutated AML.
JO  - HemaSphere
VL  - 9
IS  - 1
SN  - 2572-9241
CY  - Hoboken
PB  - John Wiley & Sons Ltd.
M1  - DKFZ-2025-00152
SP  - e70060
PY  - 2025
AB  - This study aimed to evaluate the impact of the myelodysplasia-related gene (MRG) as well as additional gene mutations on outcomes in intensively treated patients with NPM1-mutated (NPM1 mut) AML. Targeted DNA sequencing of 263 genes was performed in 568 NPM1 mut AML patients (median age: 59 years) entered into the prospective AMLSG 09-09 treatment trial. Most commonly co-mutated genes were DNMT3A (49.8
LB  - PUB:(DE-HGF)16
C6  - pmid:39816531
C2  - pmc:PMC11733593
DO  - DOI:10.1002/hem3.70060
UR  - https://inrepo02.dkfz.de/record/297977
ER  -