TY  - JOUR
AU  - Löfling, Leif Lukas
AU  - Støer, Nathalie C
AU  - Sloan, Erica K
AU  - Nafisi, Sara
AU  - Fortner, Renée Turzanski
AU  - Botteri, Edoardo
TI  - Beta-blockers and epithelial ovarian cancer survival: A Norwegian population-based cohort study.
JO  - International journal of cancer
VL  - 157
IS  - 1
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2025-00237
SP  - 86-94
PY  - 2025
N1  - 2025 Jul 1;157(1):86-94
AB  - Cancer diagnosis and therapy cause stress to the body. Preclinical studies have shown that stress hormones can stimulate tumor progression and metastasis by interacting with β-adrenergic receptors, and that β-blockers can inhibit those processes. We assessed if β-blocker use was associated with survival in a nationwide cohort of women with epithelial ovarian cancer (EOC). We identified all women aged ≥40 years who underwent EOC surgery in 2004-2018 in Norway through the Cancer Registry of Norway. We estimated the association between peri-diagnostic and post-diagnostic β-blocker use and survival. We used Cox models, adjusted for sociodemographic and health factors, and reported hazard ratios (HRs) and 95
KW  - beta‐blockers (Other)
KW  - ovarian cancer (Other)
KW  - population‐based (Other)
KW  - registry (Other)
KW  - survival (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39865612
DO  - DOI:10.1002/ijc.35348
UR  - https://inrepo02.dkfz.de/record/298230
ER  -