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@ARTICLE{Hollander:298348,
      author       = {J. F. Hollander and A. Szymansky and J. Wünschel and K.
                      Astrahantseff and C. Rosswog and A. Thorwarth and T. M.
                      Thole-Kliesch and R. Chamorro González and P. Hundsdörfer
                      and K. Hauptmann and K. Schmelz and D. Gürgen and J. M. M.
                      Rogasch and A. G. Henssen and M. Fischer and J. Schulte$^*$
                      and C. Eckert and A. Eggert$^*$ and M. Lodrini and H. E.
                      Deubzer$^*$},
      title        = {{S}erially {Q}uantifying {TERT} {R}earrangement
                      {B}reakpoints in ct{DNA} {E}nables {M}inimal {R}esidual
                      {D}isease {M}onitoring in {P}atients with {N}euroblastoma.},
      journal      = {Cancer research communications},
      volume       = {5},
      number       = {1},
      issn         = {2767-9764},
      address      = {Philadelphia, Pa.},
      publisher    = {American Association for Cancer Research},
      reportid     = {DKFZ-2025-00252},
      pages        = {167 - 177},
      year         = {2025},
      abstract     = {Real-time molecular monitoring of TERT-rearranged high-risk
                      neuroblastoma is an unmet clinical need. We tested liquid
                      biopsy-based assays for patient-individualized TERT
                      breakpoint sequences to monitor disease in pediatric
                      patients. Our digital PCR approach provides high resolution
                      of spatial and temporal disease quantification in individual
                      patients and is applicable for clinical routine.},
      keywords     = {Humans / Neuroblastoma: genetics / Neuroblastoma: pathology
                      / Telomerase: genetics / Neoplasm, Residual: genetics / Gene
                      Rearrangement: genetics / Circulating Tumor DNA: genetics /
                      Circulating Tumor DNA: blood / Liquid Biopsy: methods /
                      Biomarkers, Tumor: genetics / Biomarkers, Tumor: blood /
                      Child / Child, Preschool / Male / Telomerase (NLM Chemicals)
                      / TERT protein, human (NLM Chemicals) / Circulating Tumor
                      DNA (NLM Chemicals) / Biomarkers, Tumor (NLM Chemicals)},
      cin          = {BE01},
      ddc          = {610},
      cid          = {I:(DE-He78)BE01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39760332},
      pmc          = {pmc:PMC11774142},
      doi          = {10.1158/2767-9764.CRC-24-0569},
      url          = {https://inrepo02.dkfz.de/record/298348},
}