%0 Journal Article
%A Gandaglia, Giorgio
%A Barletta, Francesco
%A Scuderi, Simone
%A Scilipoti, Pietro
%A Rajwa, Pawel
%A Huebner, Nicolai A
%A Gomez Rivas, Juan
%A Ibanez, Laura
%A Soeterik, Timo F W
%A Bianchi, Lorenzo
%A Mattei, Agostino
%A Kesch, Claudia
%A Darr, Christopher
%A Guo, Hongqian
%A Zhuang, Junlong
%A Zattoni, Fabio
%A Fendler, Wolfgang P
%A Marra, Giancarlo
%A Stabile, Armando
%A Robesti, Daniele
%A Amparore, Daniele
%A Joniau, Steven
%A Schiavina, Riccardo
%A Sierra, Jesus Moreno
%A Porpiglia, Francesco
%A Picchio, Maria
%A Chiti, Arturo
%A Mottrie, Alexandre
%A van den Bergh, Roderick C N
%A Shariat, Shahrokh F
%A Montorsi, Francesco
%A Briganti, Alberto
%T External Validation of Nomograms for the Identification of Pelvic Nodal Dissection Candidates Among Prostate Cancer Patients with Negative Preoperative Prostate-specific Membrane Antigen Positron Emission Tomography.
%J European urology oncology
%V nn
%@ 2588-9311
%C Amsterdam
%I Elsevier
%M DKFZ-2025-00277
%P nn
%D 2025
%Z epub
%X Extended pelvic lymph node dissection (ePLND) is recommended in selected radical prostatectomy (RP) prostate cancer (PCa) patients for staging purposes. We aim to externally validate available tools to predict lymph node invasion (LNI) in men with negative preoperative prostate-specific membrane antigen positron emission tomography (miN0).Overall, 282 intermediate- to high-risk PCa patients with miN0 disease undergoing RP and ePLND at ten centers between 2016 and 2023 were identified. The Memorial Sloan Kettering Cancer Center (MSKCC); Amsterdam-Brisbane-Sydney; and Briganti 2017, 2019, and 2023 tools predicting LNI were validated externally using calibration plots, C-indexes, and decision-curve analyses to assess calibration, discrimination, and net benefit.Overall, 36 (13
%K Lymph node invasion (Other)
%K Magnetic resonance imaging–targeted biopsy (Other)
%K Nomogram (Other)
%K Pelvic lymph node dissection (Other)
%K Prostate cancer (Other)
%K Prostate-specific membrane antigen positron emission tomography (Other)
%K Radical prostatectomy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39890547
%R 10.1016/j.euo.2025.01.004
%U https://inrepo02.dkfz.de/record/298421