TY  - JOUR
AU  - Gandaglia, Giorgio
AU  - Barletta, Francesco
AU  - Scuderi, Simone
AU  - Scilipoti, Pietro
AU  - Rajwa, Pawel
AU  - Huebner, Nicolai A
AU  - Gomez Rivas, Juan
AU  - Ibanez, Laura
AU  - Soeterik, Timo F W
AU  - Bianchi, Lorenzo
AU  - Mattei, Agostino
AU  - Kesch, Claudia
AU  - Darr, Christopher
AU  - Guo, Hongqian
AU  - Zhuang, Junlong
AU  - Zattoni, Fabio
AU  - Fendler, Wolfgang P
AU  - Marra, Giancarlo
AU  - Stabile, Armando
AU  - Robesti, Daniele
AU  - Amparore, Daniele
AU  - Joniau, Steven
AU  - Schiavina, Riccardo
AU  - Sierra, Jesus Moreno
AU  - Porpiglia, Francesco
AU  - Picchio, Maria
AU  - Chiti, Arturo
AU  - Mottrie, Alexandre
AU  - van den Bergh, Roderick C N
AU  - Shariat, Shahrokh F
AU  - Montorsi, Francesco
AU  - Briganti, Alberto
TI  - External Validation of Nomograms for the Identification of Pelvic Nodal Dissection Candidates Among Prostate Cancer Patients with Negative Preoperative Prostate-specific Membrane Antigen Positron Emission Tomography.
JO  - European urology oncology
VL  - nn
SN  - 2588-9311
CY  - Amsterdam
PB  - Elsevier
M1  - DKFZ-2025-00277
SP  - nn
PY  - 2025
N1  - epub
AB  - Extended pelvic lymph node dissection (ePLND) is recommended in selected radical prostatectomy (RP) prostate cancer (PCa) patients for staging purposes. We aim to externally validate available tools to predict lymph node invasion (LNI) in men with negative preoperative prostate-specific membrane antigen positron emission tomography (miN0).Overall, 282 intermediate- to high-risk PCa patients with miN0 disease undergoing RP and ePLND at ten centers between 2016 and 2023 were identified. The Memorial Sloan Kettering Cancer Center (MSKCC); Amsterdam-Brisbane-Sydney; and Briganti 2017, 2019, and 2023 tools predicting LNI were validated externally using calibration plots, C-indexes, and decision-curve analyses to assess calibration, discrimination, and net benefit.Overall, 36 (13
KW  - Lymph node invasion (Other)
KW  - Magnetic resonance imaging–targeted biopsy (Other)
KW  - Nomogram (Other)
KW  - Pelvic lymph node dissection (Other)
KW  - Prostate cancer (Other)
KW  - Prostate-specific membrane antigen positron emission tomography (Other)
KW  - Radical prostatectomy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39890547
DO  - DOI:10.1016/j.euo.2025.01.004
UR  - https://inrepo02.dkfz.de/record/298421
ER  -