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@ARTICLE{Ehret:298582,
author = {F. Ehret$^*$ and A. R. Bhandarkar and M. Chisam and V.
Goulenko and R. Kumar and F. Fekrmandi and K. A. Skalina and
J. Kresl and S. S. Lo and I. C. Gibbs and S. G. Soltys and
J. P. Sheehan and C. Fürweger and B. J. Slotman and H. A.
Shih and S. T. Chao},
title = {{S}tereotactic {R}adiosurgery for {V}estibular {S}chwannoma
- {A} {C}ase-{B}ased {P}ractice {G}uide from the
{R}adiosurgery {S}ociety.},
journal = {Practical Radiation Oncology},
volume = {15},
number = {4},
issn = {1879-8500},
address = {Amersterdam [u.a.]},
publisher = {Elsevier},
reportid = {DKFZ-2025-00299},
pages = {335-346},
year = {2025},
note = {Volume 15, Issue 4, July–August 2025, Pages 335-346},
abstract = {Vestibular schwannomas (VS) are the most common benign
intracranial nerve sheath tumors. Surgery and radiotherapy -
particularly stereotactic radiosurgery (SRS) - are the
primary treatment options. SRS is the dominant treatment for
small- and medium-sized VS and selected larger tumors due to
its excellent local control rates and favorable safety
profile compared to surgery. However, careful treatment
planning is essential, taking into account patient
preferences, tumor location and size, symptoms, and
anticipated treatment-related toxicity.Four clinical VS
scenarios have been selected to illustrate the use of SRS,
including a unilateral, small intracanalicular VS, a large
VS with cystic components, reirradiation with SRS after
local tumor recurrence, and bilateral VS in the setting of
neurofibromatosis type 2-related schwannomatosis.SRS is an
effective and safe treatment modality for the majority of VS
cases, requiring careful treatment planning and a thorough
understanding of potential limitations and challenges.This
case-based practice guide aims to provide a concise overview
of the treatment of VS with SRS. We present and discuss four
different clinical scenarios of VS to illustrate the
pitfalls and best practice recommendations.},
keywords = {Acoustic neuroma (Other) / Radiosurgery (Other) /
Stereotactic radiosurgery (Other) / Stereotactic
radiotherapy (Other) / Vestibular schwannoma (Other)},
cin = {BE01},
ddc = {610},
cid = {I:(DE-He78)BE01-20160331},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:39909144},
doi = {10.1016/j.prro.2025.01.010},
url = {https://inrepo02.dkfz.de/record/298582},
}