%0 Journal Article
%A Lalos, Fotios
%A Flühs, Dirk
%A Guberina, Maja
%A Bornfeld, Norbert
%A Stuschke, Martin
%A Sauerwein, Wolfgang
%A Bechrakis, Nikolaos E
%T Treatment-Related Complications and Functional Results after Ruthenium-106 Brachytherapy in Small to Medium Size Uveal Melanomas (Part 2). [Behandlungsbedingte Komplikationen und funktionelle Ergebnisse nach Ruthenium-106-Brachytherapie bei kleinen bis mittelgroßen Aderhautmelanomen (Teil 2)].
%J Klinische Monatsblätter für Augenheilkunde
%V 242
%N 2
%@ 0023-2165
%C Stuttgart
%I Thieme
%M DKFZ-2025-00355
%P 116 - 126
%D 2025
%X To analyze the treatment-related complications after ruthenium-106 brachytherapy in patients with uveal melanoma in terms of radiation-induced optic neuropathy, maculopathy and retinopathy, radiation-related vitreous hemorrhage, and retinal detachment, as well as secondary glaucoma and radiogenic cataract. In addition, the course of visual acuity was analyzed.This retrospective study included 608 patients treated with ruthenium-106 brachytherapy between January 2008 and December 2010 at the Department of Ophthalmology, University Hospital Essen. The follow-up time was 11 years. The occurrence of the radiation-induced complications was analyzed using the Kaplan-Meier method. Cox regression was used for univariate and multivariate risk factor analyses. Hazard ratios were calculated for each variable.Regarding the complications, 34
%K Humans
%K Uveal Neoplasms: radiotherapy
%K Brachytherapy: adverse effects
%K Brachytherapy: methods
%K Male
%K Female
%K Melanoma: radiotherapy
%K Middle Aged
%K Radiation Injuries: etiology
%K Ruthenium Radioisotopes: therapeutic use
%K Aged
%K Adult
%K Retrospective Studies
%K Treatment Outcome
%K Aged, 80 and over
%K Young Adult
%K Risk Factors
%K Comorbidity
%K Adolescent
%K Vision Disorders: etiology
%K Incidence
%K Prevalence
%K Visual Acuity: radiation effects
%K Ruthenium Radioisotopes (NLM Chemicals)
%K Ruthenium-106 (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38395138
%R 10.1055/a-2275-5575
%U https://inrepo02.dkfz.de/record/298919