TY  - JOUR
AU  - Lalos, Fotios
AU  - Flühs, Dirk
AU  - Guberina, Maja
AU  - Bornfeld, Norbert
AU  - Stuschke, Martin
AU  - Sauerwein, Wolfgang
AU  - Bechrakis, Nikolaos E
TI  - Treatment-Related Complications and Functional Results after Ruthenium-106 Brachytherapy in Small to Medium Size Uveal Melanomas (Part 2). [Behandlungsbedingte Komplikationen und funktionelle Ergebnisse nach Ruthenium-106-Brachytherapie bei kleinen bis mittelgroßen Aderhautmelanomen (Teil 2)].
JO  - Klinische Monatsblätter für Augenheilkunde
VL  - 242
IS  - 2
SN  - 0023-2165
CY  - Stuttgart
PB  - Thieme
M1  - DKFZ-2025-00355
SP  - 116 - 126
PY  - 2025
AB  - To analyze the treatment-related complications after ruthenium-106 brachytherapy in patients with uveal melanoma in terms of radiation-induced optic neuropathy, maculopathy and retinopathy, radiation-related vitreous hemorrhage, and retinal detachment, as well as secondary glaucoma and radiogenic cataract. In addition, the course of visual acuity was analyzed.This retrospective study included 608 patients treated with ruthenium-106 brachytherapy between January 2008 and December 2010 at the Department of Ophthalmology, University Hospital Essen. The follow-up time was 11 years. The occurrence of the radiation-induced complications was analyzed using the Kaplan-Meier method. Cox regression was used for univariate and multivariate risk factor analyses. Hazard ratios were calculated for each variable.Regarding the complications, 34
KW  - Humans
KW  - Uveal Neoplasms: radiotherapy
KW  - Brachytherapy: adverse effects
KW  - Brachytherapy: methods
KW  - Male
KW  - Female
KW  - Melanoma: radiotherapy
KW  - Middle Aged
KW  - Radiation Injuries: etiology
KW  - Ruthenium Radioisotopes: therapeutic use
KW  - Aged
KW  - Adult
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - Aged, 80 and over
KW  - Young Adult
KW  - Risk Factors
KW  - Comorbidity
KW  - Adolescent
KW  - Vision Disorders: etiology
KW  - Incidence
KW  - Prevalence
KW  - Visual Acuity: radiation effects
KW  - Ruthenium Radioisotopes (NLM Chemicals)
KW  - Ruthenium-106 (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:38395138
DO  - DOI:10.1055/a-2275-5575
UR  - https://inrepo02.dkfz.de/record/298919
ER  -