TY  - JOUR
AU  - Wach, Johannes
AU  - Basaran, Alim Emre
AU  - Vychopen, Martin
AU  - Tihan, Tarik
AU  - Wostrack, Maria
AU  - Butenschoen, Vicki M
AU  - Meyer, Bernhard
AU  - Siller, Sebastian
AU  - Schmidt, Nils Ole
AU  - Onken, Julia
AU  - Vajkoczy, Peter
AU  - Santos, Alejandro N
AU  - Rauschenbach, Laurel
AU  - Dammann, Philipp
AU  - Sure, Ulrich
AU  - Klingler, Jan-Helge
AU  - Doria-Medina, Roberto
AU  - Beck, Jürgen
AU  - Blaß, Bianca-Ioana
AU  - Gizaw, Christine Juliane
AU  - Hohenhaus, Romina
AU  - Krieg, Sandro
AU  - Alhalabi, Obada T
AU  - Klein, Lukas
AU  - Thomé, Claudius
AU  - Kögl, Nikolaus
AU  - Kunert, Przemyslaw
AU  - Czernicki, Tomasz
AU  - Pantel, Tobias
AU  - Middelkamp, Maximilian
AU  - Eicker, Sven Oliver
AU  - Kattaa, Ahed H
AU  - Park, David J
AU  - Chang, Steven D
AU  - Kilinc, Fatma
AU  - Czabanka, Marcus
AU  - Güresir, Erdem
TI  - Local tumor control and neurological outcomes after surgery for spinal hemangioblastomas in sporadic and Von-Hippel-Lindau Disease: A multicenter study.
JO  - Neuro-Oncology
VL  - 27
IS  - 6
SN  - 1522-8517
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2025-00360
SP  - 1567–1578
PY  - 2025
N1  - Volume 27, Issue 6, June 2025, Pages 1567–1578
AB  - Spinal hemangioblastomas (sHBs) are rare vascular tumors with significant neurological implications. Their management, particularly in von Hippel-Lindau (VHL) disease, remains challenging due to recurrence and functional decline. Timely identification and intervention are critical for optimal outcomes.This international, multicenter retrospective cohort study included 357 patients (199 VHL-associated, 158 sporadic) from 13 neuro-oncological centers. Clinical and imaging data were analyzed to assess progression-free survival (PFS) and functional outcomes using the Modified McCormick Scale (mMCS) at 12 months. Secondary analyses identified factors associated with VHL disease in sHBs.Complete resection (CR) was achieved in 87.7
KW  - Complete resection (Other)
KW  - Multicenter study (Other)
KW  - Neurological outcomes (Other)
KW  - Progression-free survival (Other)
KW  - Spinal hemangioblastomas (Other)
KW  - Von Hippel-Lindau disease (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39950840
DO  - DOI:10.1093/neuonc/noaf041
UR  - https://inrepo02.dkfz.de/record/298926
ER  -