TY  - JOUR
AU  - Vollmuth, Philipp
AU  - Karschnia, Philipp
AU  - Sahm, Felix
AU  - Park, Yae Won
AU  - Ahn, Sung Soo
AU  - Jain, Rajan
TI  - A Radiologist's Guide to IDH-Wildtype Glioblastoma for Efficient Communication With Clinicians: Part I-Essential Information on Preoperative and Immediate Postoperative Imaging.
JO  - Korean journal of radiology
VL  - 26
IS  - 3
SN  - 1229-6929
CY  - Seoul
PB  - Society
M1  - DKFZ-2025-00442
SP  - 246-268
PY  - 2025
N1  - 2025 Mar;26(3):246-268
AB  - The paradigm of isocitrate dehydrogenase (IDH)-wildtype glioblastoma is rapidly evolving, reflecting clinical, pathological, and imaging advancements. Thus, it remains challenging for radiologists, even those who are dedicated to neuro-oncology imaging, to keep pace with this rapidly progressing field and provide useful and updated information to clinicians. Based on current knowledge, radiologists can play a significant role in managing patients with IDH-wildtype glioblastoma by providing accurate preoperative diagnosis as well as preoperative and postoperative treatment planning including accurate delineation of the residual tumor. Through active communication with clinicians, extending far beyond the confines of the radiology reading room, radiologists can impact clinical decision making. This Part 1 review provides an overview about the neuropathological diagnosis of glioblastoma to understand the past, present, and upcoming revisions of the World Health Organization classification. The imaging findings that are noteworthy for radiologists while communicating with clinicians on preoperative and immediate postoperative imaging of IDH-wildtype glioblastomas will be summarized.
KW  - Humans
KW  - Glioblastoma: diagnostic imaging
KW  - Glioblastoma: surgery
KW  - Isocitrate Dehydrogenase: genetics
KW  - Brain Neoplasms: diagnostic imaging
KW  - Brain Neoplasms: surgery
KW  - Magnetic Resonance Imaging: methods
KW  - Preoperative Care: methods
KW  - Central nervous system neoplasms (Other)
KW  - Glioblastoma (Other)
KW  - Magnetic resonance imaging (Other)
KW  - World Health Organization (Other)
KW  - Isocitrate Dehydrogenase (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:39999966
DO  - DOI:10.3348/kjr.2024.0982
UR  - https://inrepo02.dkfz.de/record/299482
ER  -