%0 Journal Article
%A Chteinberg, Emil
%A Kolarova, Julia
%A Vogt, Julia
%A Macamo, Amanda
%A Bormann, Felix
%A Kretzmer, Helene
%A Speel, Ernst Jan
%A van den Oord, Joost
%A Schneider, Christof
%A Stilgenbauer, Stephan
%A Becker, Jürgen
%A Winnepenninckx, Véronique
%A Biessen, Erik
%A Zenke, Martin
%A Kurz, Anna Kordelia
%A Siebert, Reiner
%A Zur Hausen, Axel
%T The significance of PAX5 in Merkel cell carcinoma.
%J The journal of pathology
%V 266
%N 1
%@ 0368-3494
%C Bognor Regis [u.a.]
%I Wiley
%M DKFZ-2025-00473
%P 81-94
%D 2025
%Z 2025 May;266(1):81-94
%X Merkel cell carcinoma (MCC) is a highly malignant skin cancer that expresses epithelial-, neuroendocrine-, and lymphoid-associated genes. Here, we focused on B-cell differentiation, which is characterised by the coexpression of PAX5 and TdT. PAX5 is the master regulator of B-cell commitment and is expressed in 65
%K B‐cell differentiation (Other)
%K Merkel cell carcinoma (Other)
%K PAX5 (Other)
%K epigenetics (Other)
%K transcriptomics (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40034069
%R DOI:10.1002/path.6410
%U https://inrepo02.dkfz.de/record/299515