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@ARTICLE{Meissner:299547,
      author       = {V. H. Meissner and A. Dinkel and M. Kron and S. Schiele and
                      M. Jahnen and J. Lakes and J. P. Radtke and M. A. Kuczyk and
                      N. N. Harke and J. Debus and C. A. Fink and G. Antoch and L.
                      Schimmöller and G. Kristiansen and A. Krilaviciute$^*$ and
                      P. Seibold$^*$ and S. Behrens$^*$ and A. Benner$^*$ and C.
                      Arsov and B. Hadaschik$^*$ and N. Becker$^*$ and R.
                      Kaaks$^*$ and P. Albers$^*$ and J. E. Gschwend and K.
                      Herkommer},
      title        = {{W}orry about prostate cancer and risk perception among
                      middle-aged men: results from the {PROBASE} trial.},
      journal      = {Journal of behavioral medicine},
      volume       = {48},
      number       = {3},
      issn         = {0160-7715},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer Science + Business Media B.V.},
      reportid     = {DKFZ-2025-00491},
      pages        = {464-477},
      year         = {2025},
      note         = {2025 Jun;48(3):464-477},
      abstract     = {Cancer worry and risk perception are relevant psychological
                      factors that influence preventive health behaviors.
                      Therefore, a thorough understanding of the factors that
                      impact their occurrence and manifestation is critical. The
                      objective of this study was to assess prevalence and factors
                      associated with worry about prostate cancer (PCa) and
                      absolute/comparative risk perception in a community-based
                      sample of 45-year-old men. Data were collected within the
                      German PCa screening trial PROBASE. Variables were assessed
                      by self-report questionnaires and a clinical interview.
                      Worry about PCa and absolute/comparative risk perception
                      were assessed each on a 5-point-Likert scale. Multivariable
                      logistic regression was used to identify factors associated
                      with the outcomes of interest. Data were available for
                      33,476 $(72.0\%)$ of 46,495 men at enrollment. $7.3\%$ had
                      sometimes/(very) often worry about PCa. $3.7\%$ and $9.9\%$
                      perceived their absolute risk and comparative risk as
                      somewhat high/very high and somewhat higher/much higher,
                      respectively. $18.8\%$ reported a positive PCa family
                      history. Important factors of worry about PCa, absolute risk
                      perception, and comparative risk perception were lower
                      urinary tract symptoms (LUTS) (OR 3.00, $95\%$ CI 2.63-3.42;
                      OR 2.09, CI 1.71-2.56; OR 2.41, CI 2.10-2.76) and a positive
                      PCa family history (OR 2.35, CI 2.08-2.65; OR 15.13, CI
                      12.73-17.97; OR 9.69, CI 8.76-10.72). A positive history of
                      urological (OR 3.85, CI 2.63-5.63) and non-urological
                      cancers (OR 1.97, CI 1.52-2.54) were associated with a
                      higher comparative risk perception. In conclusion, worry
                      about PCa and risk perception are influenced by
                      non-cancer-related symptoms as well as by a positive PCa
                      family history. These findings need to be addressed in risk
                      communication with patients.},
      keywords     = {Absolute risk perception (Other) / Cancer worry (Other) /
                      Comparative risk perception (Other) / Family history (Other)
                      / Lower urinary tract symptoms (Other) / Prostate cancer
                      (Other)},
      cin          = {C130 / C020 / C060 / ED01},
      ddc          = {610},
      cid          = {I:(DE-He78)C130-20160331 / I:(DE-He78)C020-20160331 /
                      I:(DE-He78)C060-20160331 / I:(DE-He78)ED01-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40042752},
      doi          = {10.1007/s10865-025-00559-w},
      url          = {https://inrepo02.dkfz.de/record/299547},
}