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@ARTICLE{Portik:300124,
      author       = {D. Portik and D. Lacombe and C. Faivre-Finn and V. Achard
                      and N. Andratschke and D. Correia and M. Spalek and M.
                      Guckenberger and P. Ost and F. Ehret$^*$},
      title        = {{T}he 2024 {S}tate of {S}cience report from the {E}uropean
                      {O}rganisation for {R}esearch and {T}reatment of {C}ancer's
                      {R}adiation {O}ncology {S}cientific {C}ouncil.},
      journal      = {European journal of cancer},
      volume       = {220},
      issn         = {0959-8049},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2025-00622},
      pages        = {115334},
      year         = {2025},
      abstract     = {Radiotherapy (RT) is a central pillar of a multimodal
                      cancer treatment approach. The ongoing advances in the
                      fields of RT, imaging technologies, cancer biology, and
                      others yield the potential to refine the use of RT. The
                      European Organisation for Research and Treatment of Cancer
                      (EORTC) hosted a dedicated workshop to identify and
                      prioritize key research questions and to define future
                      RT-based treatment strategies to improve the survival and
                      quality of life of cancer patients.An initial call for
                      relevant RT research topics led to the formation of
                      workgroups to develop these into new clinical research
                      proposals and projects. The EORTC Radiation Oncology
                      Scientific Council (ROSC) State of Science workshop was held
                      in Brussels, Belgium, in February 2024, bringing together
                      EORTC members and international stakeholders to connect and
                      work on the proposals.Four topics of interest were
                      identified: I) De-escalation of RT, minimizing toxicity
                      while maintaining patients' quality of life, II)
                      Technology-driven RT utilizing advances in treatment
                      techniques, such as spatially fractionated RT to improve
                      outcomes in patients with bulky disease and localized high
                      tumor burden, III) Biology-driven RT, integrating the rapid
                      advances in cancer biology and functional imaging to guide
                      and personalize RT, and IV) New indications adding value and
                      expanding the use of RT.The EORTC ROSC State of Science
                      workshop prioritized clinical questions to be addressed in
                      prospective clinical research projects to advance RT care
                      and improve patient outcomes.},
      keywords     = {Cancer biology (Other) / Clinical research (Other) /
                      Imaging (Other) / Organ Preservation (Other) / Radiation
                      oncology (Other) / Radiotherapy (Other) / Randomized trials
                      (Other) / Technology (Other)},
      cin          = {BE01},
      ddc          = {610},
      cid          = {I:(DE-He78)BE01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40127505},
      doi          = {10.1016/j.ejca.2025.115334},
      url          = {https://inrepo02.dkfz.de/record/300124},
}