TY  - JOUR
AU  - Wolf, Sebastian
AU  - Weber, Sarah
AU  - Janetta, Aaron
AU  - Klein, Friederike
AU  - Enssle, Julius
AU  - Hogardt, Michael
AU  - Kempf, Volkhard A J
AU  - Kessel, Johanna
AU  - Vehreschild, Maria J G T
AU  - Steffen, Björn
AU  - Oellerich, Thomas
AU  - Serve, Hubert
AU  - Scheich, Sebastian
TI  - Epidemiology and outcomes of Candida spp. bloodstream infections in cancer patients: a comparative retrospective study from a German tertiary cancer center.
JO  - Infection
VL  - nn
SN  - 0300-8126
CY  - München
PB  - Urban & Vogel
M1  - DKFZ-2025-00694
SP  - nn
PY  - 2025
N1  - epub
AB  - Bloodstream infections (BSI) due to Candida spp. significantly contribute to morbidity and mortality among cancer patients. Understanding their clinical course, risk factors, and outcomes compared to bacterial BSI is essential.We aim to elucidate the epidemiology and risk factors associated with Candida BSI compared to bacterial BSI in cancer patients.We analyzed epidemiological data of Candida BSI versus bacterial BSI among cancer patients, primarily with hematological malignancies. Blood cultures were obtained upon clinical suspicion, with species identification by VITEK 2 and MALDI-TOF. Susceptibility testing utilized VITEK 2 or antibiotic gradient tests.Candida BSI was associated with higher 30-day mortality compared to bacterial BSI (Hazard ratio (HR) 4.5, 95
KW  - Candida (Other)
KW  - Acute leukemia (Other)
KW  - Bloodstream infection (Other)
KW  - Hematology (Other)
KW  - Neutropenic fever (Other)
KW  - Oncology (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40175754
DO  - DOI:10.1007/s15010-025-02513-z
UR  - https://inrepo02.dkfz.de/record/300232
ER  -