%0 Journal Article
%A Van Bergen, Tessa D
%A Braat, Arthur J A T
%A Hermsen, Rick
%A Heetman, Joris G
%A Wever, Lieke
%A Lavalaye, Jules
%A Vinken, Maarten
%A Bahler, Clinton D
%A Tann, Mark
%A Kesch, Claudia
%A Telli, Tugce
%A Chiu, Peter Ka-Fung
%A Wu, Kwan Kit
%A Zattoni, Fabio
%A Evangelista, Laura
%A Ceci, Francesco
%A Miszczyk, Marcin
%A Rajwa, Pawel
%A Barletta, Francesco
%A Gandaglia, Giorgio
%A Van Basten, Jean-Paul A
%A Scheltema, Matthijs J
%A Van Melick, Harm H E
%A Van den Bergh, Roderick C N
%A Van den Berg, Cornelis A T
%A Marra, Giancarlo
%A Soeterik, Timo F W
%T External validation of nomograms including PSMA PET information for the prediction of lymph node involvement of prostate cancer.
%J European journal of nuclear medicine and molecular imaging
%V 52
%N 10
%@ 1619-7070
%C Heidelberg [u.a.]
%I Springer-Verl.
%M DKFZ-2025-00695
%P 3744-3756
%D 2025
%Z 2025 Aug;52(10):3744-3756
%X Novel nomograms predicting lymph node involvement (LNI) of prostate cancer (PCa) including PSMA PET information have been developed. However, their predictive accuracy in external populations is still unclear.To externally validate four LNI nomograms including PSMA PET parameters (three Muehlematter models and the Amsterdam-Brisbane-Sydney model) as well as the Briganti 2012 and MSKCC nomograms.Patients with histologically confirmed PCa undergoing preoperative MRI and PSMA PET/CT before radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND) were included. Model discrimination (AUC), calibration and net benefit using decision curve analysis were determined for each nomogram.A total of 437 patients were included, comprising 0.7
%K External validation (Other)
%K Lymph node involvement (Other)
%K Nomogram (Other)
%K PSMA PET/CT (Other)
%K Prostate cancer (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40172694
%R 10.1007/s00259-025-07241-y
%U https://inrepo02.dkfz.de/record/300233