TY  - JOUR
AU  - Van Bergen, Tessa D
AU  - Braat, Arthur J A T
AU  - Hermsen, Rick
AU  - Heetman, Joris G
AU  - Wever, Lieke
AU  - Lavalaye, Jules
AU  - Vinken, Maarten
AU  - Bahler, Clinton D
AU  - Tann, Mark
AU  - Kesch, Claudia
AU  - Telli, Tugce
AU  - Chiu, Peter Ka-Fung
AU  - Wu, Kwan Kit
AU  - Zattoni, Fabio
AU  - Evangelista, Laura
AU  - Ceci, Francesco
AU  - Miszczyk, Marcin
AU  - Rajwa, Pawel
AU  - Barletta, Francesco
AU  - Gandaglia, Giorgio
AU  - Van Basten, Jean-Paul A
AU  - Scheltema, Matthijs J
AU  - Van Melick, Harm H E
AU  - Van den Bergh, Roderick C N
AU  - Van den Berg, Cornelis A T
AU  - Marra, Giancarlo
AU  - Soeterik, Timo F W
TI  - External validation of nomograms including PSMA PET information for the prediction of lymph node involvement of prostate cancer.
JO  - European journal of nuclear medicine and molecular imaging
VL  - 52
IS  - 10
SN  - 1619-7070
CY  - Heidelberg [u.a.]
PB  - Springer-Verl.
M1  - DKFZ-2025-00695
SP  - 3744-3756
PY  - 2025
N1  - 2025 Aug;52(10):3744-3756
AB  - Novel nomograms predicting lymph node involvement (LNI) of prostate cancer (PCa) including PSMA PET information have been developed. However, their predictive accuracy in external populations is still unclear.To externally validate four LNI nomograms including PSMA PET parameters (three Muehlematter models and the Amsterdam-Brisbane-Sydney model) as well as the Briganti 2012 and MSKCC nomograms.Patients with histologically confirmed PCa undergoing preoperative MRI and PSMA PET/CT before radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND) were included. Model discrimination (AUC), calibration and net benefit using decision curve analysis were determined for each nomogram.A total of 437 patients were included, comprising 0.7
KW  - External validation (Other)
KW  - Lymph node involvement (Other)
KW  - Nomogram (Other)
KW  - PSMA PET/CT (Other)
KW  - Prostate cancer (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40172694
DO  - DOI:10.1007/s00259-025-07241-y
UR  - https://inrepo02.dkfz.de/record/300233
ER  -