TY  - JOUR
AU  - Salvador-Ribés, Carmen
AU  - Soler-Pons, Carina
AU  - Sánchez-García, María Jesús
AU  - Fechter, Tobias
AU  - Olivas, Consuelo
AU  - Torres-Espallardo, Irene
AU  - Pérez-Calatayud, José
AU  - Baltas, Dimos
AU  - Mix, Michael
AU  - Martí-Bonmatí, Luis
AU  - Carles, Montserrat
TI  - Open-source phantom with dedicated in-house software for image quality assurance in hybrid PET systems.
JO  - EJNMMI Physics
VL  - 12
IS  - 1
SN  - 2197-7364
CY  - Heidelberg
PB  - SpringerOpen
M1  - DKFZ-2025-00747
SP  - 35
PY  - 2025
AB  - Patients' diagnosis, treatment and follow-up increasingly rely on multimodality imaging. One of the main limitations for the optimal implementation of hybrid systems in clinical practice is the time and expertise required for applying standardized protocols for equipment quality assurance (QA). Experimental phantoms are commonly used for this purpose, but they are often limited to a single modality and single quality parameter, lacking automated analysis capabilities. In this study, we developed a multimodal 3D-printed phantom and software for QA in positron emission tomography (PET) hybrid systems, with computed tomography (CT) or magnetic resonance (MR), by assessing signal, spatial resolution, radiomic features, co-registration and geometric distortions.Phantom models and Python software for the proposed QA are available to download, and a user-friendly plugin compatible with the open-source 3D-Slicer software has been developed. The QA viability was proved by characterizing a Philips-Gemini-TF64-PET/CT in terms of signal response (mean, µ), intrinsic variability for three consecutive measurements (daily variation coefficient, CoVd) and reproducibility over time (variation coefficient across 5 months, CoVm). For this system, averaged recovery coefficient for activity concentration was µ = 0.90 ± 0.08 (CoVd = 0.6
KW  - 3D-printing (Other)
KW  - Experimental phantoms (Other)
KW  - Medical imaging (Other)
KW  - Oncology (Other)
KW  - PET/CT (Other)
KW  - PET/MR (Other)
KW  - Quality assurance (Other)
KW  - Radiotherapy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40192938
DO  - DOI:10.1186/s40658-025-00741-8
UR  - https://inrepo02.dkfz.de/record/300294
ER  -