% IMPORTANT: The following is UTF-8 encoded. This means that in the presence % of non-ASCII characters, it will not work with BibTeX 0.99 or older. % Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or % “biber”. @ARTICLE{Mnz:300306, author = {C. Münz and G. R. Campbell and A. Esclatine and M. Faure and P. Labonte and M. Lussignol and A. Orvedahl and N. Altan-Bonnet and R. Bartenschlager$^*$ and R. Beale and M. Cirone and L. Espert and J. Jung and D. Leib and F. Reggiori and S. Sanyal and S. A. Spector and V. Thiel and C. Viret and Y. Wei and T. Wileman and H. Wodrich}, title = {{A}utophagy machinery as exploited by viruses.}, journal = {Autophagy reports}, volume = {4}, number = {1}, issn = {2769-4127}, address = {London}, publisher = {Taylor $\&$ Francis Group}, reportid = {DKFZ-2025-00756}, pages = {2464986}, year = {2025}, abstract = {Viruses adapt and modulate cellular pathways to allow their replication in host cells. The catabolic pathway of macroautophagy, for simplicity referred to as autophagy, is no exception. In this review, we discuss anti-viral functions of both autophagy and select components of the autophagy machinery, and how viruses have evaded them. Some viruses use the membrane remodeling ability of the autophagy machinery to build their replication compartments in the cytosol or efficiently egress from cells in a non-lytic fashion. Some of the autophagy machinery components and their remodeled membranes can even be found in viral particles as envelopes or single membranes around virus packages that protect them during spreading and transmission. Therefore, studies on autophagy regulation by viral infections can reveal functions of the autophagy machinery beyond lysosomal degradation of cytosolic constituents. Furthermore, they can also pinpoint molecular interactions with which the autophagy machinery can most efficiently be manipulated, and this may be relevant to develop effective disease treatments based on autophagy modulation.}, subtyp = {Review Article}, keywords = {Endosomal damage (Other) / interferon (Other) / replication organelle (Other) / secretory autophagy (Other) / virophagy (Other)}, cin = {D430}, ddc = {610}, cid = {I:(DE-He78)D430-20160331}, pnm = {314 - Immunologie und Krebs (POF4-314)}, pid = {G:(DE-HGF)POF4-314}, typ = {PUB:(DE-HGF)16}, pubmed = {pmid:40201908}, pmc = {pmc:PMC11921968}, doi = {10.1080/27694127.2025.2464986}, url = {https://inrepo02.dkfz.de/record/300306}, }