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@ARTICLE{Marconi:300322,
      author       = {L. Marconi and T. Kuusk and M. Hora and T. Klatte and S.
                      Dabestani and U. Capitanio and Y. Abu-Ghanem and R. Campi
                      and S. Fernández-Pello and L. Albiges and J. Bedke$^*$ and
                      T. Powles and A. Volpe and B. Ljungberg and A. Bex},
      title        = {{H}ospital {V}olume as a {D}eterminant of {O}utcomes
                      {A}fter {P}artial {N}ephrectomy: {A} {S}ystematic {R}eview
                      by the {E}uropean {A}ssociation of {U}rology {R}enal {C}ell
                      {C}arcinoma {G}uidelines {P}anel.},
      journal      = {European urology oncology},
      volume       = {8},
      number       = {3},
      issn         = {2588-9311},
      address      = {Amsterdam},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2025-00768},
      pages        = {25},
      year         = {2025},
      note         = {2025 Jun;8(3):616-622},
      abstract     = {The influence of surgical volume on partial nephrectomy
                      (PN) outcomes is a subject of debate. The European
                      Association of Urology (EAU) renal cell carcinoma (RCC)
                      guideline panel performed a protocol-driven systematic
                      review of the association between hospital volume (HV) and
                      oncological, functional, and complication outcomes following
                      PN for RCC. The intervention was PN performed in a
                      higher-volume hospital (defined according to the number of
                      procedures per unit time) and the comparator was PN
                      performed in a lower-volume hospital. Ten studies involving
                      a total of 106 569 patients were included in the review.
                      Higher HV was associated with lower complication rates,
                      shorter length of stay, lower positive surgical margin
                      rates, and lower transfusion rates. For six studies,
                      multivariable analyses showed that low HV was an independent
                      risk factor for inpatient complications, PSM presence,
                      longer LOS, and failure to achieve a trifecta of no
                      complications, warm ischemia time <25 min, and negative
                      surgical margins. Most studies were judged to have high risk
                      of bias. The available evidence suggests a potential
                      association between higher HV and better PN outcomes in RCC.
                      The EAU RCC guidelines panel encourages the development and
                      rigorous evaluation of indicators of surgery quality in RCC
                      to better inform the designation of high-quality centers
                      within models of centralized care.},
      keywords     = {Evidence synthesis (Other) / High-volume center (Other) /
                      Hospital volume (Other) / Learning curve (Other) / Partial
                      nephrectomy (Other) / Referral center (Other) / Renal cell
                      cancer (Other) / Systematic review (Other)},
      cin          = {TU01},
      ddc          = {610},
      cid          = {I:(DE-He78)TU01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40210551},
      doi          = {10.1016/j.euo.2025.01.013},
      url          = {https://inrepo02.dkfz.de/record/300322},
}