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@ARTICLE{Schallenberg:300327,
      author       = {S. Schallenberg and M. Schulte and M.-P. Dragomir$^*$ and
                      A. Jarosch and W. Hartmann and E. Wardelmann},
      title        = {{F}rom benign appearance to malignant truth: a case report
                      of mesenteric dedifferentiated liposarcoma with inflammatory
                      myofibroblastic tumor-like features.},
      journal      = {Diagnostic pathology},
      volume       = {20},
      number       = {1},
      issn         = {1746-1596},
      address      = {[Erscheinungsort nicht ermittelbar]},
      publisher    = {BioMed Central},
      reportid     = {DKFZ-2025-00773},
      pages        = {39},
      year         = {2025},
      abstract     = {Dedifferentiated liposarcoma (DDLPS) with inflammatory
                      myofibroblastic tumor (IMT)-like features is a rare and
                      diagnostically challenging variant of soft tissue sarcoma.
                      We report the case of a 74-year-old man who presented with a
                      mesenteric mass in 2022 and recurrent tumors in 2024. Tissue
                      from both primary and recurrent tumors were submitted to our
                      reference center for pathological reevaluation, with a
                      suspicion of IMT being suspected. Although the tumors
                      exhibited morphological characteristics consistent with
                      those observed in IMT, they displayed distinctive
                      histological, immunohistochemical and molecular features
                      suggestive of DDLPS with IMT-like features, including
                      amplification of the MDM2 gene. This report highlights the
                      morphological spectrum of DDLPS, the diagnostic role of
                      molecular pathology, and the importance of differentiating
                      this aggressive neoplasm from benign entities such as IMT.},
      keywords     = {Humans / Male / Liposarcoma: pathology / Liposarcoma:
                      diagnosis / Liposarcoma: genetics / Aged / Mesentery:
                      pathology / Proto-Oncogene Proteins c-mdm2: genetics /
                      Biomarkers, Tumor: analysis / Biomarkers, Tumor: genetics /
                      Immunohistochemistry / Diagnosis, Differential / Soft Tissue
                      Neoplasms: pathology / Neoplasm Recurrence, Local: pathology
                      / Peritoneal Neoplasms: pathology / Neoplasms, Muscle
                      Tissue: pathology / Neoplasms, Muscle Tissue: diagnosis /
                      Proto-Oncogene Proteins c-mdm2 (NLM Chemicals) / Biomarkers,
                      Tumor (NLM Chemicals) / MDM2 protein, human (NLM Chemicals)},
      cin          = {BE01},
      ddc          = {610},
      cid          = {I:(DE-He78)BE01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40211332},
      doi          = {10.1186/s13000-025-01640-3},
      url          = {https://inrepo02.dkfz.de/record/300327},
}