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000300573 1001_ $$00009-0003-4795-1807$$aVladimirov, Sergei$$b0
000300573 245__ $$aIncidence and clinical outcomes of ventilator-associated events in Russian tertiary care settings: an analysis of electronic health records.
000300573 260__ $$aLondon$$b[Verlag nicht ermittelbar]$$c2025
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000300573 520__ $$aThis research aimed to evaluate the epidemiological and clinical characteristics of ventilator-associated events (VAE) using the CDC framework in a tertiary hospital in Moscow, Russia.In this cohort study, we analyzed electronic health records from 407 mechanically ventilated adults who were admitted to the Kommunarka Moscow Multipurpose Clinical Center between September 2022 and December 2023. We identified a total of 35 VAE, resulting in an incidence rate of 8.39 (95% confidence interval, 5.84 to 11.67) events per 1,000 ventilator-days. The presence of VAE was associated with higher ICU mortality by day 30 from the start of mechanical ventilation (adjusted hazard ratio, 1.58; 95% confidence interval, 1.01 to 2.48), particularly in patients with infection-related ventilator-associated complications (adjusted hazard ratio, 2.09; 95% confidence interval, 1.17 to 3.74). The median durations of mechanical ventilation and ICU length of stay were comparable between patients with VAE and those without. Implementing surveillance measures and developing tailored preventive strategies for VAE may be beneficial in similar healthcare settings to improve outcomes for mechanically ventilated patients.
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000300573 650_7 $$2Other$$aEpidemiology
000300573 650_7 $$2Other$$aInfection-related complication
000300573 650_7 $$2Other$$aIntensive care
000300573 650_7 $$2Other$$aMechanical ventilation
000300573 650_7 $$2Other$$aVentilator-associated event
000300573 650_7 $$2Other$$aVentilator-associated pneumonia
000300573 650_2 $$2MeSH$$aHumans
000300573 650_2 $$2MeSH$$aFemale
000300573 650_2 $$2MeSH$$aMale
000300573 650_2 $$2MeSH$$aMiddle Aged
000300573 650_2 $$2MeSH$$aRespiration, Artificial: adverse effects
000300573 650_2 $$2MeSH$$aElectronic Health Records: statistics & numerical data
000300573 650_2 $$2MeSH$$aIncidence
000300573 650_2 $$2MeSH$$aAged
000300573 650_2 $$2MeSH$$aTertiary Care Centers: statistics & numerical data
000300573 650_2 $$2MeSH$$aIntensive Care Units: statistics & numerical data
000300573 650_2 $$2MeSH$$aLength of Stay: statistics & numerical data
000300573 650_2 $$2MeSH$$aPneumonia, Ventilator-Associated: epidemiology
000300573 650_2 $$2MeSH$$aAdult
000300573 650_2 $$2MeSH$$aHospital Mortality
000300573 650_2 $$2MeSH$$aMoscow: epidemiology
000300573 650_2 $$2MeSH$$aRussia: epidemiology
000300573 7001_ $$aKlimenko, Ilia$$b1
000300573 7001_ $$00000-0001-7066-7175$$aMatiushkov, Nikita$$b2
000300573 7001_ $$00000-0002-5166-3280$$aProtsenko, Denis$$b3
000300573 7001_ $$0P:(DE-He78)772c4cbbab31f1b71f814e8ae9e0ed51$$aSergeev, Dmitry$$b4$$eLast author$$udkfz
000300573 773__ $$0PERI:(DE-600)2413336-X$$a10.1186/s13104-025-07240-0$$gVol. 18, no. 1, p. 172$$n1$$p172$$tBMC Research Notes$$v18$$x1756-0500$$y2025
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