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024 7 _ |a 10.1186/s13104-025-07240-0
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037 _ _ |a DKFZ-2025-00806
041 _ _ |a English
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100 1 _ |a Vladimirov, Sergei
|0 0009-0003-4795-1807
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245 _ _ |a Incidence and clinical outcomes of ventilator-associated events in Russian tertiary care settings: an analysis of electronic health records.
260 _ _ |a London
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520 _ _ |a This research aimed to evaluate the epidemiological and clinical characteristics of ventilator-associated events (VAE) using the CDC framework in a tertiary hospital in Moscow, Russia.In this cohort study, we analyzed electronic health records from 407 mechanically ventilated adults who were admitted to the Kommunarka Moscow Multipurpose Clinical Center between September 2022 and December 2023. We identified a total of 35 VAE, resulting in an incidence rate of 8.39 (95% confidence interval, 5.84 to 11.67) events per 1,000 ventilator-days. The presence of VAE was associated with higher ICU mortality by day 30 from the start of mechanical ventilation (adjusted hazard ratio, 1.58; 95% confidence interval, 1.01 to 2.48), particularly in patients with infection-related ventilator-associated complications (adjusted hazard ratio, 2.09; 95% confidence interval, 1.17 to 3.74). The median durations of mechanical ventilation and ICU length of stay were comparable between patients with VAE and those without. Implementing surveillance measures and developing tailored preventive strategies for VAE may be beneficial in similar healthcare settings to improve outcomes for mechanically ventilated patients.
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650 _ 7 |a Epidemiology
|2 Other
650 _ 7 |a Infection-related complication
|2 Other
650 _ 7 |a Intensive care
|2 Other
650 _ 7 |a Mechanical ventilation
|2 Other
650 _ 7 |a Ventilator-associated event
|2 Other
650 _ 7 |a Ventilator-associated pneumonia
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Respiration, Artificial: adverse effects
|2 MeSH
650 _ 2 |a Electronic Health Records: statistics & numerical data
|2 MeSH
650 _ 2 |a Incidence
|2 MeSH
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Tertiary Care Centers: statistics & numerical data
|2 MeSH
650 _ 2 |a Intensive Care Units: statistics & numerical data
|2 MeSH
650 _ 2 |a Length of Stay: statistics & numerical data
|2 MeSH
650 _ 2 |a Pneumonia, Ventilator-Associated: epidemiology
|2 MeSH
650 _ 2 |a Adult
|2 MeSH
650 _ 2 |a Hospital Mortality
|2 MeSH
650 _ 2 |a Moscow: epidemiology
|2 MeSH
650 _ 2 |a Russia: epidemiology
|2 MeSH
700 1 _ |a Klimenko, Ilia
|b 1
700 1 _ |a Matiushkov, Nikita
|0 0000-0001-7066-7175
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700 1 _ |a Protsenko, Denis
|0 0000-0002-5166-3280
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700 1 _ |a Sergeev, Dmitry
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773 _ _ |a 10.1186/s13104-025-07240-0
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