%0 Journal Article
%A Onyedibe, Maria Chidi Christiana
%A Schmidt, Martina
%A Bizer, Pauline
%A Zimmer, Philipp
%A Steindorf, Karen
%T Subjective and Objective Cancer-Related Cognitive Impairments Among Systemic and Radiation Therapy-Naïve Female Cancer Patients.
%J Cancer medicine
%V 14
%N 8
%@ 2045-7634
%C Hoboken, NJ
%I Wiley
%M DKFZ-2025-00845
%P e70908
%D 2025
%Z #EA:C110#LA:C110#
%X Cancer-related cognitive impairment (CRCI) is a frequent and burdensome problem that is still insufficiently understood and managed. We investigated subjective and objective measures of CRCI, as recommended by the International Cancer and Cognition Task Force (ICCTF) in cancer patients prior to systemic or radiation therapy with respect to potential influencing or associated psychosocial, demographic, or lifestyle factors.Female patients with breast or gynecological tumors (n = 239, mean age = 55.5, SD = 11.6) prior to any systemic or radiation therapy completed validated subjective (FACT-Cog: perceived cognitive impairment [PCI], perceived cognitive ability [PCA], impact on quality of life [IQoL]) and objective measures of CRCI (Trail Making Test [TMT-A and -B], Controlled Oral Word Association Test [COWA], and Hopkins Verbal Learning Test-Revised [HVLT-R]). Association with cross-sectionally assessed age, body mass index, education, smoking, alcohol intake, sleep problems, social support, anxiety, and pain was investigated using multiple linear regression models.A quarter (25.1
%K Humans
%K Female
%K Middle Aged
%K Quality of Life
%K Aged
%K Cognitive Dysfunction: etiology
%K Cognitive Dysfunction: epidemiology
%K Cognitive Dysfunction: diagnosis
%K Cognitive Dysfunction: psychology
%K Adult
%K Breast Neoplasms: complications
%K Breast Neoplasms: psychology
%K Breast Neoplasms: therapy
%K Cross-Sectional Studies
%K Genital Neoplasms, Female: complications
%K Genital Neoplasms, Female: psychology
%K Genital Neoplasms, Female: therapy
%K Neuropsychological Tests
%K anxiety (Other)
%K breast cancer (Other)
%K cancer‐related cognitive impairment (Other)
%K neuropsychological tests (Other)
%K sleep problem (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40259875
%R 10.1002/cam4.70908
%U https://inrepo02.dkfz.de/record/300631