TY  - JOUR
AU  - Onyedibe, Maria Chidi Christiana
AU  - Schmidt, Martina
AU  - Bizer, Pauline
AU  - Zimmer, Philipp
AU  - Steindorf, Karen
TI  - Subjective and Objective Cancer-Related Cognitive Impairments Among Systemic and Radiation Therapy-Naïve Female Cancer Patients.
JO  - Cancer medicine
VL  - 14
IS  - 8
SN  - 2045-7634
CY  - Hoboken, NJ
PB  - Wiley
M1  - DKFZ-2025-00845
SP  - e70908
PY  - 2025
N1  - #EA:C110#LA:C110#
AB  - Cancer-related cognitive impairment (CRCI) is a frequent and burdensome problem that is still insufficiently understood and managed. We investigated subjective and objective measures of CRCI, as recommended by the International Cancer and Cognition Task Force (ICCTF) in cancer patients prior to systemic or radiation therapy with respect to potential influencing or associated psychosocial, demographic, or lifestyle factors.Female patients with breast or gynecological tumors (n = 239, mean age = 55.5, SD = 11.6) prior to any systemic or radiation therapy completed validated subjective (FACT-Cog: perceived cognitive impairment [PCI], perceived cognitive ability [PCA], impact on quality of life [IQoL]) and objective measures of CRCI (Trail Making Test [TMT-A and -B], Controlled Oral Word Association Test [COWA], and Hopkins Verbal Learning Test-Revised [HVLT-R]). Association with cross-sectionally assessed age, body mass index, education, smoking, alcohol intake, sleep problems, social support, anxiety, and pain was investigated using multiple linear regression models.A quarter (25.1
KW  - Humans
KW  - Female
KW  - Middle Aged
KW  - Quality of Life
KW  - Aged
KW  - Cognitive Dysfunction: etiology
KW  - Cognitive Dysfunction: epidemiology
KW  - Cognitive Dysfunction: diagnosis
KW  - Cognitive Dysfunction: psychology
KW  - Adult
KW  - Breast Neoplasms: complications
KW  - Breast Neoplasms: psychology
KW  - Breast Neoplasms: therapy
KW  - Cross-Sectional Studies
KW  - Genital Neoplasms, Female: complications
KW  - Genital Neoplasms, Female: psychology
KW  - Genital Neoplasms, Female: therapy
KW  - Neuropsychological Tests
KW  - anxiety (Other)
KW  - breast cancer (Other)
KW  - cancer‐related cognitive impairment (Other)
KW  - neuropsychological tests (Other)
KW  - sleep problem (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40259875
DO  - DOI:10.1002/cam4.70908
UR  - https://inrepo02.dkfz.de/record/300631
ER  -