TY  - JOUR
AU  - Carletti, Filippo
AU  - Maggi, Martina
AU  - Fazekas, Tamas
AU  - Rajwa, Pawel
AU  - Nicoletti, Rossella
AU  - Olivier, Jonathan
AU  - Preisser, Felix
AU  - Soeterik, Timo F W
AU  - Giganti, Francesco
AU  - Martini, Alberto
AU  - Heidegger, Isabel
AU  - Kasivisvanathan, Veeru
AU  - Pradère, Benjamin
AU  - Ploussard, Guillaume
AU  - Hadaschik, Boris
AU  - Moro, Fabrizio Dal
AU  - van den Bergh, Roderick C N
AU  - Marra, Giancarlo
AU  - Gandaglia, Giorgio
AU  - Zattoni, Fabio
AU  - Kesch, Claudia
TI  - Diagnostic accuracy of multiparametric MRI for detecting unconventional prostate cancer histology: a systematic review and meta-analysis.
JO  - European radiology
VL  - 36
IS  - 1
SN  - 0938-7994
CY  - Heidelberg
PB  - Springer
M1  - DKFZ-2025-00899
SP  - 17-29
PY  - 2026
N1  - 2026 Jan;36(1):17-29 / Epub 2025 Apr 30
AB  - Accurate detection of unconventional histologies (UH) in prostate cancer (PCa) is crucial for treatment planning and prognosis. This systematic review and meta-analysis aimed to evaluate the accuracy of multiparametric magnetic resonance imaging (mpMRI) in detecting UH on prostatectomy, particularly cribriform architecture (CA) and intraductal carcinoma (IDC-P), in patients with localized PCa.A literature search was conducted in major databases for studies published after 2000. Seventeen articles fulfilled the inclusion criteria and were eligible for qualitative analysis. Five studies met the inclusion criteria for meta-analysis.The pooled sensitivity and specificity of mpMRI (Prostate Imaging Reporting and Data System (PI-RADS) cutoff 3) to detect cribriform architecture were 0.91 and 0.29. The proportion of cribriform lesions increased with higher PI-RADS scores (23.2
LB  - PUB:(DE-HGF)16
C6  - pmid:40307530
DO  - DOI:10.1007/s00330-025-11603-3
UR  - https://inrepo02.dkfz.de/record/300739
ER  -