%0 Journal Article
%A Støer, Nathalie C
%A Botteri, Edoardo
%A Lindemann, Kristina
%A Langseth, Hilde
%A Turzanski-Fortner, Renée
%T Low-dose aspirin and non-aspirin non-steroidal anti-inflammatory drugs and epithelial ovarian cancer survival: a registry-based cohort study in Norway.
%J BMC cancer
%V 25
%N 1
%@ 1471-2407
%C London
%I BioMed Central
%M DKFZ-2025-00905
%P 807
%D 2025
%Z #LA:C020#
%X Aspirin and non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAID) have been associated with improved survival in individuals with epithelial ovarian cancer (EOC); however, findings to date are inconsistent.We conducted a registry-based cohort study evaluating survival following an incident invasive EOC diagnosis including individuals diagnosed between 2004-2018 (n = 4325; n = 2206 deaths; n = 1973 EOC deaths). Evaluated exposures were low-dose aspirin and NA-NSAIDs. Two primary post-diagnosis exposure windows were evaluated: fixed post-diagnostic baseline exposure ≤ 305 days after diagnosis (use, non-use) and updated 'time-varying' exposure (never, past, current use; cumulative defined daily dose (DDD)). Pre-diagnostic exposure (use, non-use) was further evaluated. Multivariable Cox-proportional hazard models were used to estimate hazard ratios (HRs) and 95
%K Humans
%K Female
%K Aspirin: administration & dosage
%K Aspirin: therapeutic use
%K Anti-Inflammatory Agents, Non-Steroidal: administration & dosage
%K Anti-Inflammatory Agents, Non-Steroidal: therapeutic use
%K Carcinoma, Ovarian Epithelial: mortality
%K Carcinoma, Ovarian Epithelial: drug therapy
%K Registries: statistics & numerical data
%K Norway: epidemiology
%K Middle Aged
%K Aged
%K Ovarian Neoplasms: mortality
%K Ovarian Neoplasms: drug therapy
%K Cohort Studies
%K Adult
%K Proportional Hazards Models
%K Aspirin (Other)
%K Non-aspirin NSAIDs (Other)
%K Ovarian cancer (Other)
%K Survival (Other)
%K Aspirin (NLM Chemicals)
%K Anti-Inflammatory Agents, Non-Steroidal (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40307814
%R 10.1186/s12885-025-14168-y
%U https://inrepo02.dkfz.de/record/300745