%0 Journal Article
%A Lee, Sojung
%A Ho, Yin Yee
%A Hao, Suyu
%A Ouyang, Yingqi
%A Liew, U Ling
%A Goyal, Ashish
%A Li, Stephen
%A Barbour, Jayne A
%A He, Mu
%A Huang, Yuanhua
%A Wong, Jason W H
%T A tumour necrosis factor-α responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7.
%J The journal of biological chemistry
%V 301
%N 6
%@ 0021-9258
%C Bethesda, Md.
%I Soc.
%M DKFZ-2025-00922
%P 108568
%D 2025
%Z Volume 301, Issue 6, June 2025, 108568
%X Endogenous retroviruses (ERVs) shape human genome functionality and influence disease pathogenesis, including cancer. ERVK-7, a significant ERV, acts as an immune modulator and prognostic marker in lung adenocarcinoma (LUAD). Although ERVK-7 overexpression has been linked to the amplification of the 1q22 locus in approximately 10
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40316021
%R 10.1016/j.jbc.2025.108568
%U https://inrepo02.dkfz.de/record/300774