TY  - JOUR
AU  - Lee, Sojung
AU  - Ho, Yin Yee
AU  - Hao, Suyu
AU  - Ouyang, Yingqi
AU  - Liew, U Ling
AU  - Goyal, Ashish
AU  - Li, Stephen
AU  - Barbour, Jayne A
AU  - He, Mu
AU  - Huang, Yuanhua
AU  - Wong, Jason W H
TI  - A tumour necrosis factor-α responsive cryptic promoter drives overexpression of the human endogenous retrovirus ERVK-7.
JO  - The journal of biological chemistry
VL  - 301
IS  - 6
SN  - 0021-9258
CY  - Bethesda, Md.
PB  - Soc.
M1  - DKFZ-2025-00922
SP  - 108568
PY  - 2025
N1  - Volume 301, Issue 6, June 2025, 108568
AB  - Endogenous retroviruses (ERVs) shape human genome functionality and influence disease pathogenesis, including cancer. ERVK-7, a significant ERV, acts as an immune modulator and prognostic marker in lung adenocarcinoma (LUAD). Although ERVK-7 overexpression has been linked to the amplification of the 1q22 locus in approximately 10
LB  - PUB:(DE-HGF)16
C6  - pmid:40316021
DO  - DOI:10.1016/j.jbc.2025.108568
UR  - https://inrepo02.dkfz.de/record/300774
ER  -