TY  - JOUR
AU  - Earl, Julie
AU  - Kataki, Agapi
AU  - Canzian, Federico
AU  - Costello, Eithne
AU  - Campa, Daniele
AU  - Greenhalf, William
TI  - Targeting pancreatic cancer screening by identification of pathogenic variants of BRCA2/ BRCA1 in healthy individuals who have no known family history of pancreatic cancer: The arguments for and against.
JO  - Seminars in cancer biology
VL  - 113
SN  - 1044-579X
CY  - London
PB  - Academic Press
M1  - DKFZ-2025-00958
SP  - 1 - 8
PY  - 2025
AB  - The majority of patients with pancreatic ductal adenocarcinoma (PDAC) are no longer suitable for treatment with curable intent at the time of diagnosis resulting in a 5-year survival of less than 10 
KW  - BRCA1 (Other)
KW  - BRCA2 (Other)
KW  - Cancer risk (Other)
KW  - Germline mutation (Other)
KW  - Screening (Other)
KW  - Surveillance (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40339999
DO  - DOI:10.1016/j.semcancer.2025.05.001
UR  - https://inrepo02.dkfz.de/record/301273
ER  -