TY  - JOUR
AU  - Trautwein, Nils F
AU  - Mattern, Sven
AU  - Hinterleitner, Martina
AU  - Reischl, Gerald
AU  - Schirrmacher, Ralf
AU  - Steger, Volker
AU  - Nadalin, Silvio
AU  - Nikolaou, Konstantin
AU  - Schwenck, Johannes
AU  - Singer, Stephan
AU  - la Fougère, Christian
TI  - Histologic Ex Vivo Validation of the [18F]SITATE Somatostatin Receptor PET Tracer.
JO  - Journal of nuclear medicine
VL  - 66
IS  - 8
SN  - 0097-9058
CY  - New York, NY
PB  - Soc.
M1  - DKFZ-2025-01062
SP  - 1204-1209
PY  - 2025
N1  - 2025 Aug 1;66(8):1204-1209
AB  - Radiolabeled somatostatin analogs (SSAs), such as [68Ga]Ga-DOTA SSAs, have transformed imaging and therapeutic strategies. However, their use is constrained by the high cost of generators and their short half-life. In contrast, [18F]SITATE presents a promising alternative, offering the advantage of a longer half-life than 68Ga, along with the cost-effectiveness of cyclotron-based production. This study evaluated the first histologic ex vivo validation of [18F]SITATE. Methods: This study retrospectively included 47 patients (57
KW  - PET (Other)
KW  - SSTR PET (Other)
KW  - [18F]SITATE (Other)
KW  - neuroendocrine neoplasms (Other)
KW  - oncology (Other)
KW  - radiotracer tissue kinetics (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40404394
DO  - DOI:10.2967/jnumed.125.269619
UR  - https://inrepo02.dkfz.de/record/301541
ER  -