TY  - JOUR
AU  - Toussaint, Laura
AU  - Tram Henriksen, Louise
AU  - Van Beek, Karen
AU  - Bolle, Stephanie
AU  - Demoor-Goldschmidt, Charlotte
AU  - Gains, Jenny
AU  - Høyer, Morten
AU  - Janssens, Geert O
AU  - Kortmann, Rolf-Dieter
AU  - Martins Pedro, Catia
AU  - Timmermann, Beate
AU  - Scheinemann, Katrin
AU  - Lassen-Ramshad, Yasmin
TI  - European practice on neurovascular late effects after pediatric radiotherapy: considerations on dose planning and follow-up - a HARMONIC/SIOPE ROWG survey.
JO  - Acta oncologica
VL  - 64
SN  - 0284-186X
CY  - Abingdon
PB  - Taylor & Francis Group
M1  - DKFZ-2025-01070
SP  - 703 - 707
PY  - 2025
AB  - The risk of developing neurovascular late effects after radiotherapy is an area of concern when treating pediatric brain tumor patients. However, knowledge is sparse regarding best practice for clinical management during the radiotherapy (RT) planning process and follow-up examinations. This study therefore aimed at mapping how the risk of neurovascular late effects is considered for pediatric brain or skull base tumor patients treated with radiotherapy in Europe.Two web-based surveys ‑ a RT and a pediatric oncology (PO) survey - were distributed to members of the SIOPE radiotherapy working group or PANCARE and SIOPE brain tumor group, respectively.The RT survey was completed by 47 participants from 18 different European countries and the PO survey by 33 participants (mostly pediatric (neuro)oncologists) from 15 countries. Overall, the answers highlighted that neurovascular late effects are currently not well included in European clinical practice, neither at the time of radiotherapy nor in the follow-up process.There is a need for raising general awareness about the topic, as well as for potential risk-stratified prevention measures and follow-up guidelines.
KW  - Humans
KW  - Europe
KW  - Child
KW  - Follow-Up Studies
KW  - Brain Neoplasms: radiotherapy
KW  - Radiotherapy Planning, Computer-Assisted: methods
KW  - Radiation Injuries: etiology
KW  - Radiation Injuries: prevention & control
KW  - Radiation Injuries: epidemiology
KW  - Surveys and Questionnaires
KW  - Radiotherapy Dosage
KW  - Skull Base Neoplasms: radiotherapy
KW  - Practice Patterns, Physicians': statistics & numerical data
KW  - Female
KW  - Male
LB  - PUB:(DE-HGF)16
C6  - pmid:40402041
DO  - DOI:10.2340/1651-226X.2025.43028
UR  - https://inrepo02.dkfz.de/record/301549
ER  -