TY - JOUR
AU - Torres-Laiton, Luisa
AU - Luján-Barroso, Leila
AU - Nadal-Zaragoza, Núria
AU - Castro-Espin, Carlota
AU - Jakszyn, Paula
AU - Panico, Camilla
AU - Le Cornet, Charlotte
AU - Dahm, Christina C
AU - Petrova, Dafina
AU - Rodríguez-Palacios, Daniel Ángel
AU - Jannasch, Franziska
AU - Masala, Giovanna
AU - Dossus, Laure
AU - Padroni, Lisa
AU - Guevara, Marcela
AU - Schulze, Matthias B
AU - Fortner, Renée T
AU - Tumino, Rosario
AU - Crous-Bou, Marta
TI - Diabetes-Related Dietary Patterns and Endometrial Cancer Risk and Survival in the European Prospective Investigation into Cancer and Nutrition Study.
JO - Nutrients
VL - 17
IS - 10
SN - 2072-6643
CY - Basel
PB - MDPI
M1 - DKFZ-2025-01108
SP - 1645
PY - 2025
AB - Endometrial cancer (EC)'s major risk factors include obesity and diabetes, both strongly related with lifestyle choices and dietary factors. Our study aimed to evaluate the relationship between diabetes-related dietary patterns, EC risk, and survival in a population of middle-aged European women.A total of 285,418 female participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study were included in the analysis. After a mean time of 10.6 years of follow-up, 1955 incident EC cases were registered; of those, 133 women died from EC. The Empirical Dietary Index for Insulin Resistance (EDIR), the Empirical Dietary Index for Hyperinsulinemia (EDIH), and the Diabetes Risk Reduction Diet (DRRD), were estimated from dietary information collected at baseline from EPIC participants. Cox proportional hazards regression models were used to evaluate the association between the dietary patterns and EC risk, using hazard ratios (HR), 95
KW - Humans
KW - Female
KW - Endometrial Neoplasms: mortality
KW - Endometrial Neoplasms: epidemiology
KW - Endometrial Neoplasms: etiology
KW - Middle Aged
KW - Prospective Studies
KW - Europe: epidemiology
KW - Risk Factors
KW - Diet: adverse effects
KW - Proportional Hazards Models
KW - Feeding Behavior
KW - Diabetes Mellitus: epidemiology
KW - Adult
KW - Insulin Resistance
KW - Diabetes Mellitus, Type 2
KW - diabetes (Other)
KW - dietary patterns (Other)
KW - endometrial cancer (Other)
KW - etiology (Other)
KW - risk factors (Other)
KW - survival (Other)
LB - PUB:(DE-HGF)16
C6 - pmid:40431387
C2 - pmc:PMC12114188
DO - DOI:10.3390/nu17101645
UR - https://inrepo02.dkfz.de/record/301716
ER -