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000301718 1001_ $$0P:(DE-He78)4e4e534b615747750de8b9a7afdd8f56$$aTeleanu, Maria-Veronica$$b0$$eFirst author$$udkfz
000301718 245__ $$aCelebrating Ulrik Ringborg: Multi-Omics-Based Patient Stratification for Precision Cancer Treatment.
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000301718 500__ $$a#EA:B340#LA:B340# / 2025 May 10;15(5):693
000301718 520__ $$aPrecision oncology is becoming a mainstay in the standard of care for cancer patients. Recent technological advancements have significantly lowered the cost of various tumor profiling approaches, broadening the reach of molecular diagnostics and improving patient access to precision oncology. In parallel, drug development and discovery pipelines continue to evolve, driving targeted therapeutic options forward. Yet, not all patients harboring actionable molecular alterations respond to these interventions, and existing therapies do not cover the entire spectrum of potential molecular targets. In this review, we examine the current suite of omics technologies employed in clinical settings and underscore their roles in deepening our understanding of tumor biology and optimizing patient stratification for targeted treatments. We also highlight relevant precision oncology trials and share our own experiences using multi-omics data within a molecular tumor board framework. Finally, we discuss areas for future exploration aimed at propelling precision oncology to new heights.
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000301718 650_7 $$2Other$$amolecular profiling
000301718 650_7 $$2Other$$apatient stratification
000301718 650_7 $$2Other$$aprecision oncology
000301718 650_2 $$2MeSH$$aHumans
000301718 650_2 $$2MeSH$$aPrecision Medicine: methods
000301718 650_2 $$2MeSH$$aNeoplasms: genetics
000301718 650_2 $$2MeSH$$aNeoplasms: metabolism
000301718 650_2 $$2MeSH$$aNeoplasms: drug therapy
000301718 650_2 $$2MeSH$$aNeoplasms: therapy
000301718 650_2 $$2MeSH$$aGenomics: methods
000301718 650_2 $$2MeSH$$aProteomics: methods
000301718 650_2 $$2MeSH$$aMultiomics
000301718 7001_ $$0P:(DE-He78)01467978dd6fe4c28888cc8a5109cd35$$aSchneider, Annika$$b1$$udkfz
000301718 7001_ $$0P:(DE-He78)7a10ea1b9b2872da9f375002c44ddfce$$aBall, Claudia$$b2
000301718 7001_ $$0P:(DE-He78)1401445b374879f90e840ca2e6a96bac$$aLeber, Mathias Felix$$b3$$udkfz
000301718 7001_ $$0P:(DE-He78)5c7b30aaeb7a74a0dee50c5cc776b143$$aStange, Christoph$$b4$$udkfz
000301718 7001_ $$0P:(DE-He78)8e2078af783ff2be822e7799c43bc86a$$aKrieghoff-Henning, Eva$$b5$$udkfz
000301718 7001_ $$0P:(DE-He78)f6b238ac374345c55706521c4f435779$$aBeck, Katja$$b6
000301718 7001_ $$0P:(DE-He78)42b6114cd48e033299b2b6ef4bf56cc6$$aHeilig, Christoph E$$b7$$udkfz
000301718 7001_ $$0P:(DE-He78)e5972dddc3c8d1412db29ba54fed83ba$$aKreutzfeldt, Simon$$b8
000301718 7001_ $$00000-0002-9094-1677$$aKuster, Bernhard$$b9
000301718 7001_ $$0P:(DE-He78)c403a040c97f91902a7d31b93859f9fc$$aLipka, Daniel$$b10$$udkfz
000301718 7001_ $$0P:(DE-He78)f0144d171d26dbedb67c9db1df35629d$$aFröhling, Stefan$$b11$$eLast author
000301718 773__ $$0PERI:(DE-600)2701262-1$$a10.3390/biom15050693$$gVol. 15, no. 5, p. 693 -$$n5$$p693$$tBiomolecules$$v15$$x2218-273X$$y2025
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