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@ARTICLE{Sanz:301774,
      author       = {Y. Sanz and J. F. Cryan and M. Deschasaux-Tanguy and E.
                      Elinav$^*$ and R. Lambrecht and P. Veiga},
      title        = {{T}he gut microbiome connects nutrition and human health.},
      journal      = {Nature reviews / Gastroenterology $\&$ hepatology},
      volume       = {22},
      number       = {8},
      issn         = {1759-5045},
      address      = {Basingstoke},
      publisher    = {Nature Publishing Group},
      reportid     = {DKFZ-2025-01154},
      pages        = {534-555},
      year         = {2025},
      note         = {2025 Aug;22(8):534-555},
      abstract     = {The gut microbiome has an undeniable role in mediating the
                      health effects of the diet, given its ability to co-digest
                      nutrients and influence nutrient signalling to multiple
                      organ systems. As a suboptimal diet is a major risk factor
                      for and contributor to disease, understanding the
                      multidirectional interactions between the food we eat, the
                      gut microbiome and the different body organ systems is
                      crucial from a public health perspective. Indeed, this
                      research area is leading to the refinement of nutritional
                      concepts and strategies to optimize health through diet. In
                      this Review, we provide an update on how dietary patterns
                      and food intake shape gut microbiome features, the mode of
                      action of diet-microorganism interactions on the immune,
                      nervous and cardiometabolic systems and how this knowledge
                      could explain the heterogeneity of dietary responses, and
                      support food-based dietary guidelines and medical and
                      precision nutrition. Finally, we discuss the knowledge gaps
                      and research efforts needed to progress towards the
                      integration of microbiome science with more precise dietary
                      advice to leverage the role of nutrition in human health.},
      subtyp        = {Review Article},
      cin          = {D480},
      ddc          = {610},
      cid          = {I:(DE-He78)D480-20160331},
      pnm          = {314 - Immunologie und Krebs (POF4-314)},
      pid          = {G:(DE-HGF)POF4-314},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40468006},
      doi          = {10.1038/s41575-025-01077-5},
      url          = {https://inrepo02.dkfz.de/record/301774},
}