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@ARTICLE{Riemann:302117,
      author       = {L. T. Riemann and M. Ataian and F. P. S. Hähner and B.
                      Roth$^*$ and A. Knurr$^*$ and A. Kamitz and M. Christopeit
                      and C. Bokemeyer and F. Ückert},
      title        = {{S}treamlining and {A}ccelerating the {M}olecular {T}umor
                      {B}oard {P}rocess at the {U}niversity {M}edical {C}enter
                      {H}amburg-{E}ppendorf.},
      journal      = {Targeted oncology},
      volume       = {20},
      issn         = {1776-2596},
      address      = {Paris},
      publisher    = {Springer Verlag France S.A.R.L.},
      reportid     = {DKFZ-2025-01249},
      pages        = {725–735},
      year         = {2025},
      note         = {Volume 20, pages 725–735},
      abstract     = {We developed, introduced, and evaluated Molecular ONcology
                      Optimized CLinical Evaluation (MONOCLE), a secure,
                      open-source web application at the University Medical Center
                      Hamburg-Eppendorf (UKE), to optimize the analysis and
                      discussion of complex cancer cases in molecular tumor boards
                      (MTB).MONOCLE standardizes and harmonizes documentation,
                      while its integrated Knowledge Connector accelerates
                      literature research for personalized treatment.The system
                      was designed by merging the requirements of the German
                      Network for Personalized Medicine (DNPM), the medical staff
                      involved in the MTB process, and the team developing
                      MONOCLE. The usability was evaluated using the System
                      Usability Scale (SUS) and user tasks. Overall process
                      optimization was measured by the number of automated tasks
                      that can be performed.MONOCLE, introduced into clinical
                      practice in June 2024, significantly reduces time for
                      documentation, as three manual steps now run automatically,
                      and transfer of the data to the DNPM is possible. Its
                      usability and SUS showed positive results, ranging between
                      92.5 and 97.5.As the first open-source and extendable
                      solution for standardized MTB documentation, MONOCLE enables
                      wider adoption by other medical centers.},
      cin          = {M130},
      ddc          = {610},
      cid          = {I:(DE-He78)M130-20160331},
      pnm          = {312 - Funktionelle und strukturelle Genomforschung
                      (POF4-312)},
      pid          = {G:(DE-HGF)POF4-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:40526350},
      doi          = {10.1007/s11523-025-01160-6},
      url          = {https://inrepo02.dkfz.de/record/302117},
}