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@ARTICLE{Hennrich:302329,
author = {U. Hennrich$^*$ and L. Wagner$^*$ and H. Tas$^*$ and L.
Kovacs$^*$ and M. Benesova-Schäfer$^*$},
title = {{R}evolutionizing {P}rostate {C}ancer {D}etection: {T}he
{R}ole of {A}pproved {PSMA}-{PET} {I}maging {A}gents.},
journal = {Pharmaceuticals},
volume = {18},
number = {6},
issn = {1424-8247},
address = {Basel},
publisher = {MDPI},
reportid = {DKFZ-2025-01324},
pages = {906},
year = {2025},
note = {#EA:W630#LA:E270#},
abstract = {Locametz®/Illuccix®/GozellixTM (Novartis AG (Basel,
Switzerland) and Telix Pharmaceuticals, Ltd. (Melbourne,
Australia), all three [68Ga]Ga-PSMA-11),
Pylarify®/Pylclari® (Progenics Pharmaceuticals, Inc. (New
York, USA) and Curium PET France SA (Paris, France), both
[18F]DCFPyL), Radelumin® (ABX GmbH (Radeberg, Germany),
[18F]PSMA-1007), and Posluma® (Blue Earth Diagnostics, Ltd.
(Oxford, UK), [18F]rhPSMA-7.3) are four approved PSMA-PET
imaging agents that have significantly advanced the
diagnosis and management of prostate cancer. These agents
offer a new level of precision and accuracy, enabling
clinicians to detect prostate cancer with enhanced
sensitivity. As a result, they play a critical role in
improving detection, staging, and management, ultimately
enhancing clinical outcomes for patients. Their use in
routine clinical practice is expected to increase diagnostic
precision and provide clearer pathways for personalized
therapy. This review offers a comprehensive chemical,
pharmaceutical, and medicinal overview, discusses
comparative studies, and highlights additional highly
relevant candidates for prostate cancer detection.},
subtyp = {Review Article},
keywords = {EMA approval (Other) / FDA approval (Other) / GozellixTM
(Other) / Illuccix® (Other) / Locametz® (Other) / PET
diagnostics (Other) / PSMA (Other) / Posluma® (Other) /
Pylarify® (Other) / Pylclari® (Other) / Radelumin®
(Other) / fluorine-18 (Other) / gallium-68 (Other) /
prostate cancer (Other)},
cin = {W630 / E270},
ddc = {610},
cid = {I:(DE-He78)W630-20160331 / I:(DE-He78)E270-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40573302},
doi = {10.3390/ph18060906},
url = {https://inrepo02.dkfz.de/record/302329},
}