TY  - JOUR
AU  - Thomann, Benedikt
AU  - Fechter, Tobias
AU  - Fischer, Johannes
AU  - Runz, Armin
AU  - Roers, Julian
AU  - Ludwig, Ute
AU  - Grehn, Melanie
AU  - Grohmann, Maximilian
AU  - Ziemann, Christian
AU  - Judge, Michael
AU  - Baus, Wolfgang
AU  - Grahle, Michelle
AU  - Walke, Matthias
AU  - Bathen, Bastian
AU  - Köhn, Janett
AU  - Käthner, Paul
AU  - Shariff, Maya
AU  - Matthis, Rebecca
AU  - Fleckenstein, Jens
AU  - Großmann, Sascha
AU  - Streller, Tino
AU  - Howitz, Simon
AU  - Priegnitz, Marlen
AU  - Weigel, Rocco
AU  - Winkler, Peter
AU  - Blanck, Oliver
AU  - Schmitt, Daniela
AU  - Beck, Jurgen
AU  - Machein, Marcia
AU  - Pappas, Evangelos
AU  - Popp, Ilinca
AU  - Reiner, Michael
AU  - Karger, Christian
AU  - Moustakis, Christos
AU  - Bock, Michael
AU  - Grosu, Anca-Ligia
AU  - Baltas, Dimos
TI  - Multicenter multiplatform pattern-of-practice analysis of single-isocenter multitarget stereotactic radiosurgery.
JO  - Strahlentherapie und Onkologie
VL  - 201
IS  - 9
SN  - 0179-7158
CY  - Heidelberg
PB  - Springer Medizin
M1  - DKFZ-2025-01376
SP  - 953-962
PY  - 2025
N1  - 2025 Sep;201(9):953-962
AB  - Single-isocenter multitarget stereotactic radiosurgery (SIMT SRS) offers enhanced clinical efficiency for treating multiple brain metastases. However, it introduces additional uncertainties, such as off-center dose and beam profile inaccuracies, as well as quality assurance (QA) challenges, complicating its implementation. This study aims to evaluate different SIMT SRS approaches.We collected and analyzed SIMT SRS protocol and infrastructure parameters from 23 radiotherapy centers across Germany, Austria, and Switzerland, encompassing immobilization systems, computed tomography (CT) protocols, linear accelerators, treatment planning systems, beam configurations, imaging techniques, and QA practices. Consensus, deviations, and compliance with current guidelines were assessed. Subsequent studies will include on-site measurements, evaluation of treatment plan quality and delivery accuracy, and correlation of these findings with the analyzed protocols to identify potential links between protocol parameters and clinical outcomes.There is consensus (at least 80
KW  - Anthropomorphic phantom (Other)
KW  - Brain metastases (Other)
KW  - End-to-end test (Other)
KW  - Ring trial (Other)
KW  - SIMT SRS (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40637729
DO  - DOI:10.1007/s00066-025-02424-w
UR  - https://inrepo02.dkfz.de/record/302836
ER  -