%0 Journal Article
%A Kenkhuis, Marlou-Floor
%A Doorenbos, Meike
%A Mast, Isa H
%A Aaronson, Neil K
%A van Beurden, Marc
%A Bohus, Martin
%A Courneya, Kerry S
%A Daley, Amanda J
%A Galvão, Daniel A
%A Goedendorp, Martine M
%A van Harten, Wim H
%A Hayes, Sandi C
%A Hiensch, Anouk E
%A Irwin, Melinda L
%A Kersten, Marie José
%A Knoop, Hans
%A May, Anne M
%A McConnachie, Alex
%A van Mechelen, Willem
%A Mutrie, Nanette
%A Newton, Robert U
%A Nollet, Frans
%A Oldenburg, Hester S
%A Schmidt, Martina
%A Schmitz, Kathryn H
%A Schulz, Karl-Heinz
%A Sonke, Gabe S
%A Steindorf, Karen
%A Stuiver, Martijn M
%A Taaffe, Dennis R
%A Thorsen, Lene
%A Velthuis, Miranda J
%A Wiskemann, Joachim
%A Mesters, Ilse
%A Ulrich, Cornelia M
%A van Vulpen, Jonna K
%A Custers, Jose A E
%A Buffart, Laurien M
%T Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.
%J Supportive care in cancer
%V 33
%N 7
%@ 0941-4355
%C New York,NY
%I Springer
%M DKFZ-2025-01405
%P 647
%D 2025
%X This study aimed to investigate whether socio-demographic, clinical, and intervention-related variables moderate the effects of exercise on depression and anxiety symptoms in cancer survivors.Data from 26 RCTs in the POLARIS database were analyzed using a one-step individual participant data (IPD) meta-analytic approach with linear mixed models to assess exercise effects on depression and anxiety symptoms (z-scores). Interaction terms were added to these models to explore moderators. Results are presented as betas (corresponding to Cohen's d effect size).Albeit statistically significant, exercise demonstrated negligible effects on symptoms of depression (β = - 0.11; 95
%K Humans
%K Anxiety: therapy
%K Anxiety: etiology
%K Depression: therapy
%K Depression: etiology
%K Exercise: psychology
%K Randomized Controlled Trials as Topic
%K Male
%K Female
%K Neoplasms: psychology
%K Cancer Survivors: psychology
%K Middle Aged
%K Survivors: psychology
%K Exercise Therapy: methods
%K Adult
%K Anxiety (Other)
%K Cancer survivors (Other)
%K Depression (Other)
%K Distress (Other)
%K Exercise (Other)
%K Moderators (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40591016
%2 pmc:PMC12213934
%R 10.1007/s00520-025-09646-9
%U https://inrepo02.dkfz.de/record/302865