TY  - JOUR
AU  - Kenkhuis, Marlou-Floor
AU  - Doorenbos, Meike
AU  - Mast, Isa H
AU  - Aaronson, Neil K
AU  - van Beurden, Marc
AU  - Bohus, Martin
AU  - Courneya, Kerry S
AU  - Daley, Amanda J
AU  - Galvão, Daniel A
AU  - Goedendorp, Martine M
AU  - van Harten, Wim H
AU  - Hayes, Sandi C
AU  - Hiensch, Anouk E
AU  - Irwin, Melinda L
AU  - Kersten, Marie José
AU  - Knoop, Hans
AU  - May, Anne M
AU  - McConnachie, Alex
AU  - van Mechelen, Willem
AU  - Mutrie, Nanette
AU  - Newton, Robert U
AU  - Nollet, Frans
AU  - Oldenburg, Hester S
AU  - Schmidt, Martina
AU  - Schmitz, Kathryn H
AU  - Schulz, Karl-Heinz
AU  - Sonke, Gabe S
AU  - Steindorf, Karen
AU  - Stuiver, Martijn M
AU  - Taaffe, Dennis R
AU  - Thorsen, Lene
AU  - Velthuis, Miranda J
AU  - Wiskemann, Joachim
AU  - Mesters, Ilse
AU  - Ulrich, Cornelia M
AU  - van Vulpen, Jonna K
AU  - Custers, Jose A E
AU  - Buffart, Laurien M
TI  - Exercise effects on symptoms of depression and anxiety vary by patient, clinical, and intervention characteristics in cancer survivors: Results from pooled analyses of individual participant data of 26 RCTs.
JO  - Supportive care in cancer
VL  - 33
IS  - 7
SN  - 0941-4355
CY  - New York,NY
PB  - Springer
M1  - DKFZ-2025-01405
SP  - 647
PY  - 2025
AB  - This study aimed to investigate whether socio-demographic, clinical, and intervention-related variables moderate the effects of exercise on depression and anxiety symptoms in cancer survivors.Data from 26 RCTs in the POLARIS database were analyzed using a one-step individual participant data (IPD) meta-analytic approach with linear mixed models to assess exercise effects on depression and anxiety symptoms (z-scores). Interaction terms were added to these models to explore moderators. Results are presented as betas (corresponding to Cohen's d effect size).Albeit statistically significant, exercise demonstrated negligible effects on symptoms of depression (β = - 0.11; 95
KW  - Humans
KW  - Anxiety: therapy
KW  - Anxiety: etiology
KW  - Depression: therapy
KW  - Depression: etiology
KW  - Exercise: psychology
KW  - Randomized Controlled Trials as Topic
KW  - Male
KW  - Female
KW  - Neoplasms: psychology
KW  - Cancer Survivors: psychology
KW  - Middle Aged
KW  - Survivors: psychology
KW  - Exercise Therapy: methods
KW  - Adult
KW  - Anxiety (Other)
KW  - Cancer survivors (Other)
KW  - Depression (Other)
KW  - Distress (Other)
KW  - Exercise (Other)
KW  - Moderators (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:40591016
C2  - pmc:PMC12213934
DO  - DOI:10.1007/s00520-025-09646-9
UR  - https://inrepo02.dkfz.de/record/302865
ER  -